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需要治疗的早产儿视网膜病变风险计算器。

Risk Calculator for Retinopathy of Prematurity Requiring Treatment.

作者信息

Chaves-Samaniego Maria J, García Castejón Mar, Chaves-Samaniego Maria C, Solans Perez Larraya Ana, Ortega Molina Jose Maria, Muñoz Hoyos Antonio, García-Serrano Jose L

机构信息

Doctoral Program in Clinical Medicine and Public Health, University of Granada, Granada, Spain.

Department of Ophthalmology, San Cecilio University Hospital, Granada, Spain.

出版信息

Front Pediatr. 2020 Sep 18;8:529639. doi: 10.3389/fped.2020.529639. eCollection 2020.

Abstract

Vascular delay that occurs early in the development of retinopathy of prematurity (ROP) is a risk factor that can be compensated by ensuring a good rate of retinal vascularization to avoid ROP that requires treatment. The objective of the present study was to determine the association between ROP that requires treatment and risk factors such as the extent of the temporal avascular area of the retina and the number of days of mechanical ventilation (MV). Observational retrospective case-control study. Two hundred and twenty-eight premature newborns included in the screening protocol for retinopathy of prematurity. Subjects underwent retinal examination in the 4 and 6th postnatal weeks. : The temporal avascular area was measured in disc diameters (DD), while the MV time was measured in days of treatment. Patients with a longer MV time had a higher risk of treatment ( : 24.7, < 0.0001; increase in risk of 8.1% for each additional day), as did those who showed greater avascular area ( : 24.7, < 0.0001; increase in risk of 111% for each additional DD). An online calculator system and a table are presented for calculating the risk of ROP requiring treatment as a function of these two risk factors. The temporal avascular area of the retina and MV time must be taken into account in the first examination of the newborn to predict the need for ROP treatment.

摘要

早产儿视网膜病变(ROP)早期出现的血管延迟是一个风险因素,可通过确保良好的视网膜血管化速率来弥补,以避免需要治疗的ROP。本研究的目的是确定需要治疗的ROP与视网膜颞侧无血管区范围和机械通气(MV)天数等风险因素之间的关联。观察性回顾性病例对照研究。228名纳入早产儿视网膜病变筛查方案的早产儿。在出生后第4周和第6周对受试者进行视网膜检查。视网膜颞侧无血管区以视盘直径(DD)测量,MV时间以治疗天数测量。MV时间较长的患者接受治疗的风险较高(比值比:24.7,P<0.0001;每增加一天风险增加8.1%),视网膜无血管区较大的患者也是如此(比值比:24.7,P<0.0001;每增加一个DD风险增加111%)。给出了一个在线计算器系统和一个表格,用于根据这两个风险因素计算需要治疗的ROP风险。在新生儿首次检查时,必须考虑视网膜颞侧无血管区和MV时间,以预测ROP治疗的需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74c8/7530187/cc7569f451dc/fped-08-529639-g0001.jpg

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