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与生物传感技术相关的新型冠状病毒肺炎研究进展:病毒检测与监测的新机遇

Current progress on COVID-19 related to biosensing technologies: New opportunity for detection and monitoring of viruses.

作者信息

Laghrib F, Saqrane S, El Bouabi Y, Farahi A, Bakasse M, Lahrich S, El Mhammedi M A

机构信息

Sultan Moulay Slimane University, Laboratory of Chemistry, Modeling and Environmental Sciences, Polydisciplinary Faculty, 25 000 Khouribga, Morocco.

Ibn Zohr University, Team of Catalysis and Environment, Faculty of Sciences, BP 8106 Agadir, Morocco.

出版信息

Microchem J. 2021 Jan;160:105606. doi: 10.1016/j.microc.2020.105606. Epub 2020 Oct 8.

Abstract

The technologies used for coronavirus testing consist of a pre-existing device developed to examine different pathologies, such as bacterial infections, or cancer biomarkers. However, for the 2019 pandemic, researchers knew that their technology could be modified to detect a low viral load at an early stage. Today, countries around the world are working to control the new coronavirus disease (n-SARS-CoV-2). From this perspective, laboratories, universities, and companies around the world have embarked on a race to develop and produce much-needed test kits. This review has been developed to provide an overview of current trends and strategies in n-SARS-CoV-2 diagnostics based on traditional and new emerging assessment technologies, to continuous innovation. It focuses on recent trends in biosensors to build a fast, reliable, more sensitive, accessible, user-friendly system and easily adaptable technology n-SARS-CoV-2 detection and monitoring. On the whole, we have addressed and identified research evidence supporting the use of biosensors on the premise that screening people for n-SARS-CoV-2 is the best way to contain its spread.

摘要

用于新冠病毒检测的技术包括一种预先存在的设备,该设备是为检测不同的病理状况而开发的,比如细菌感染或癌症生物标志物。然而,对于2019年的疫情,研究人员知道他们的技术可以进行修改,以便在早期阶段检测到低病毒载量。如今,世界各国都在努力控制新型冠状病毒病(n-SARS-CoV-2)。从这个角度来看,世界各地的实验室、大学和公司都已展开竞赛,以开发和生产急需的检测试剂盒。本综述旨在基于传统和新兴的评估技术,对n-SARS-CoV-2诊断的当前趋势和策略进行概述,以实现持续创新。它聚焦于生物传感器的最新趋势,以构建一个快速、可靠、更灵敏、可及、用户友好的系统以及易于适配的技术用于n-SARS-CoV-2的检测和监测。总体而言,我们在筛查n-SARS-CoV-2感染者是遏制其传播的最佳方式这一前提下,探讨并确定了支持使用生物传感器的研究证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3df/7543751/5caa70f2fafd/gr1_lrg.jpg

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