Nene Ajinkya, Geng Shengyong, Zhou Wenhua, Yu Xue-Feng, Luo Hongrong, Ramakrishna Seeram
Materials Interfaces Center, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, China.
Center for Nanofibers and Nanotechnology, National University of Singapore, 117576, Singapore.
Curr Med Chem. 2023;30(8):935-952. doi: 10.2174/0929867329666220225110302.
Black phosphorus nanostructures (nano-BPs) mainly include BP nanosheets (BP NSs), BP quantum dots (BPQDs), and other nano-BPs-based particles at nanoscale. Firstly discovered in 2014, nano-BPs are one of the most popular nanomaterials. Different synthesis methods are discussed in short to understand the basic concepts and developments in synthesis. Exfoliated nano-BPs, i.e. nano-BPs possess high surface area, high photothermal conversion efficacy, excellent biocompatibility, high charge carrier mobility (~1000 cmVs), thermal conductivity of 86 WmK; and these properties make it a highly potential candidate for fabrication of biosensing platform. These properties enable nano-BPs to be promising photothermal/drug delivery agents as well as in electrochemical data storage devices and sensing devices; and in super capacitors, photodetectors, photovoltaics and solar cells, LEDs, super-conductors, etc. Early diagnosis is very critical in the health sector scenarios. This review attempts to highlight the attempts made towards attaining stable BP, BP-aptamer conjugates for successful biosensing applications. BP-aptamer- based platforms are reviewed to highlight the significance of BP in detecting biological and physiological markers of cardiovascular diseases and cancer; to be useful in disease diagnosis and management.
黑磷纳米结构（nano-BPs）主要包括黑磷纳米片（BP NSs）、黑磷量子点（BPQDs）以及其他基于纳米尺度的黑磷纳米结构颗粒。纳米黑磷于2014年首次被发现，是最受欢迎的纳米材料之一。本文简要讨论了不同的合成方法，以了解合成方面的基本概念和进展。剥离的纳米黑磷，即纳米黑磷具有高表面积、高光热转换效率、优异的生物相容性、高载流子迁移率（约1000 cmVs）、86 WmK的热导率；这些特性使其成为制造生物传感平台的极具潜力的候选材料。这些特性使纳米黑磷成为有前景的光热/药物递送剂，以及用于电化学数据存储设备和传感设备；以及用于超级电容器、光电探测器、光伏和太阳能电池、发光二极管、超导体等。在卫生领域的情况下，早期诊断非常关键。本综述试图突出为实现用于成功生物传感应用的稳定黑磷、黑磷适配体缀合物所做的努力。对基于黑磷适配体的平台进行了综述，以突出黑磷在检测心血管疾病和癌症的生物和生理标志物方面的重要性；对疾病诊断和管理有用。
