Laboratory for Separation Processes and Product Design, Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ulica 17, SI-2000 Maribor, Slovenia.
Department of Food and Biotechnology, Faculty of Technology and Metallurgy, Ss. Cyril and Methodius University in Skopje, Rudjer Boskovic 16, 1000 Skopje, Republic of Macedonia.
Molecules. 2020 Oct 15;25(20):4735. doi: 10.3390/molecules25204735.
Phytochemical research based on ethnopharmacology is gaining interest in industries such as functional food, nutraceuticals, cosmetics and pharmaceutical industries. Plants and plant extracts are a rich source of bioactive secondary metabolites. These compounds are often involved in plant protection against biotic or abiotic stresses. The exploitation of available technologies should be oriented and intensified to extend and enhance the continued usefulness of the plants as renewable sources of chemicals, especially medicinal compounds. This current contribution is focused on extraction and analytical techniques for their isolation from the oregano species, their characterization and their potential antioxidative, as well as their antimicrobial, antifungal and anticarcinogenic properties. The work is structured rendering to the different steps involved in the research; starting with extraction and sample preparation, followed by discussing the analytical techniques employed for the isolation and identification of compound/s responsible for the biological activity and methods and techniques for biological activity assessment.
基于民族药理学的植物化学研究在功能食品、营养保健品、化妆品和制药等行业引起了关注。植物和植物提取物是生物活性次生代谢物的丰富来源。这些化合物通常参与植物对生物或非生物胁迫的保护。应定向和加强利用现有技术，以扩大和增强植物作为化学品的可再生资源的持续利用，特别是药用化合物。本研究重点介绍了从牛至属植物中提取和分析技术，用于分离、鉴定其特征以及潜在的抗氧化、抗菌、抗真菌和抗癌特性。本工作按照研究中涉及的不同步骤进行组织；从提取和样品制备开始，然后讨论用于分离和鉴定负责生物活性的化合物/的分析技术，以及生物活性评估的方法和技术。
