Yavarian Jila, Shafiei-Jandaghi Nazanin-Zahra, Sadeghi Kaveh, Shatizadeh Malekshahi Somayeh, Salimi Vahid, Nejati Ahmad, Aja-Minejad Fatemeh, Ghavvami Nastaran, Saadatmand Fatemeh, Mahfouzi Saeedeh, Fateminasab Ghazal, Parhizgari Najmeh, Ahmadi Akramsadat, Razavi Kobra, Ghabeshi Soad, Saberian Mostafa, Zanjani Elham, Namazi Fatemeh, Shahbazi Tayebeh, Rezaie Farshid, Erfani Hossein, Gouya Mohammad Mehdi, Nasr Dadras Mohammad, Mokhtari Azad Talat
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Department of Virology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Iran J Public Health. 2020 Aug;49(8):1564-1568. doi: 10.18502/ijph.v49i8.3903.
In Jan 2020, the outbreak of the 2019 novel coronavirus (SARS-CoV-2) in Wuhan, Hubei Province of China spread increasingly to other countries worldwide which WHO declared it as a public health emergency of international concern. Iran was included in the affected countries. Throat swab specimens were collected and tested by using real-time reverse transcription PCR (RT-PCR) kit targeting the E region for screening and RNA dependent RNA polymerase for confirmation. Conventional RT-PCR was conducted for the N region and the PCR products were sequenced by Sanger sequencing. The first seven cases of SARS-CoV-2 infections were identified in Qom, Iran. This report describes the clinical and epidemiological features of the first cases of SARS-CoV-2 confirmed in Iran. Future research should focus on finding the routes of transmission for this virus, including the possibility of transmission from foreign tourists to identify the possible origin of SARS-CoV-2 outbreak in Iran.
2020年1月，中国湖北省武汉市爆发的2019新型冠状病毒（SARS-CoV-2）疫情日益蔓延至全球其他国家，世界卫生组织宣布这是一场国际关注的突发公共卫生事件。伊朗被列入受影响国家。采集了咽喉拭子样本，并使用针对E区域的实时逆转录聚合酶链反应（RT-PCR）试剂盒进行检测以进行筛查，同时使用依赖RNA的RNA聚合酶进行确认。对N区域进行常规RT-PCR，并通过桑格测序对PCR产物进行测序。在伊朗库姆发现了首批7例SARS-CoV-2感染病例。本报告描述了伊朗首批确诊的SARS-CoV-2病例的临床和流行病学特征。未来的研究应集中于寻找该病毒的传播途径，包括外国游客传播的可能性，以确定伊朗SARS-CoV-2疫情的可能源头。
