1Department of Pediatrics, Federal Medical Center, Katsina, Nigeria.
2Department of Family Medicine, Federal Medical Center, Katsina, Nigeria.
Am J Trop Med Hyg. 2020 Dec;103(6):2376-2381. doi: 10.4269/ajtmh.20-0759. Epub 2020 Oct 26.
There is a paucity of information regarding the epidemiology and outcome of COVID-19 from low/middle-income countries, including from Nigeria. This single-center study described the clinical features, laboratory findings, and predictors of in-hospital mortality of COVID-19 patients. Patients admitted between April 10, 2020 and June 10, 2020 were included. Forty-five patients with a mean age of 43 (16) years, predominantly male (87%), presented with fever (38%), cough (29%), or dyspnea (24%). In-hospital mortality was 16%. The independent predictors of mortality were hypoxemia (adjusted odds ratio [aOR]: 2.5; 95% CI: 1.3-5.1) and creatinine > 1.5 mg/dL (aOR: 4.3; 95% CI: 1.9-9.8).
关于来自包括尼日利亚在内的低收入和中等收入国家的 COVID-19 的流行病学和结局的信息十分匮乏。这项单中心研究描述了 COVID-19 患者的临床特征、实验室发现和住院死亡率的预测因素。患者纳入时间为 2020 年 4 月 10 日至 2020 年 6 月 10 日。45 名患者的平均年龄为 43（16）岁，主要为男性（87%），表现为发热（38%）、咳嗽（29%）或呼吸困难（24%）。住院死亡率为 16%。死亡的独立预测因素是低氧血症（调整后的优势比[aOR]：2.5；95%置信区间[CI]：1.3-5.1）和肌酐＞1.5 mg/dL（aOR：4.3；95% CI：1.9-9.8）。
