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精神分裂症或双相情感障碍患者的就业状况:一项基于人群的全国登记研究。

Employment among people with schizophrenia or bipolar disorder: A population-based study using nationwide registers.

机构信息

Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

出版信息

Acta Psychiatr Scand. 2021 Jan;143(1):61-71. doi: 10.1111/acps.13254. Epub 2020 Nov 24.

Abstract

OBJECTIVE

To assess the employment rate and the related background factors among people with schizophrenia or bipolar disorder.

METHODS

We identified all people in Sweden aged 18-64 years diagnosed with schizophrenia or bipolar disorder in nationwide registers in the years 2006-2013. The identified individuals were grouped by main activity or source of income. The association between background factors and employment was analyzed with generalized estimating equations (GEE).

RESULTS

Three years before the first psychosis or bipolar disorder diagnosis, 24% of the individuals with schizophrenia and 45% of the individuals with bipolar disorder were employed. However, the employment rate dropped around the time of the first diagnosis. Five years later, 10% of the individuals with schizophrenia and 34% of the individuals with bipolar disorder were employed. The most important factors associated with employment after diagnosis were a high level of education, older age at the first registered diagnosis, no substance use disorder, and a low number of previous hospitalizations. Marriage or cohabiting, higher level of education, and higher age at the first diagnosis were associated with an increased employment rate especially among people with schizophrenia, and substance use was associated with a lower employment rate, especially among people with bipolar disorder. Men with bipolar disorder had a higher employment rate than women.

CONCLUSION

The employment rate is low among people with schizophrenia and higher among people with bipolar disorder. The association of background characteristics with employment was mostly in the same direction both in schizophrenia and in bipolar disorder.

摘要

目的

评估精神分裂症或双相情感障碍患者的就业率及其相关背景因素。

方法

我们在全国登记册中确定了所有在 2006 年至 2013 年期间被诊断为精神分裂症或双相情感障碍的瑞典 18-64 岁人群。根据主要活动或收入来源对确定的个体进行分组。使用广义估计方程(GEE)分析背景因素与就业之间的关系。

结果

在首次出现精神病或双相情感障碍之前的 3 年,24%的精神分裂症患者和 45%的双相情感障碍患者有工作。然而,就业率在首次诊断时下降。5 年后,10%的精神分裂症患者和 34%的双相情感障碍患者有工作。与诊断后就业相关的最重要因素是受教育程度较高、首次登记诊断时年龄较大、无物质使用障碍和先前住院次数较少。婚姻或同居、受教育程度较高和首次诊断时年龄较大与精神分裂症患者的就业率增加有关,而物质使用与双相情感障碍患者的就业率较低有关。双相情感障碍男性的就业率高于女性。

结论

精神分裂症患者的就业率较低,而双相情感障碍患者的就业率较高。背景特征与就业之间的关联在精神分裂症和双相情感障碍中基本一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b98/7839734/8e339bdd5e57/ACPS-143-61-g001.jpg

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