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COVID-19 肺炎 CT 应用、方案和辐射剂量的变化:来自国际原子能机构研究的 28 个国家的结果。

Variations in CT Utilization, Protocols, and Radiation Doses in COVID-19 Pneumonia: Results from 28 Countries in the IAEA Study.

机构信息

From the Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 75 Blossom Ct, Room 248, Boston, MA 02114 (F.H., M.K.K.); Radiation Protection of Patients Unit, International Atomic Energy Agency, Vienna, Austria (O.H., J.V.); The Royal Hospital, Muscat, Oman (R.A.U.); Alfa Scan Radiology Center, Cairo, Egypt (S.A.); Department of Radiology, Lithuanian University of Health Sciences, Kaunas, Lithuania (A.B.); Institute of Physics, University of São Paulo, São Paulo, Brazil (P.R.C.); Hamad Medical Corporation, Doha, Qatar (A.D.); Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University, Skopje, North Macedonia (V.G.); Tartu University Hospital, University of Tartu, Institute of Clinical Medicine, Department of Radiology, Tartu, Estonia (P.I.); Aleksandrovska University Hospital, Sofia, Bulgaria (D.K.L.); Institute of Radioprotection and Dosimetry, National Nuclear Energy Commission, Rio de Janeiro, Brazil (S.K.R.); Radiology Department, Firouzgar Hospital, Iran University of Medical Sciences, Tehran, Iran (I.M.); Medical Physics Unit, A.O.U. Città della Salute e della Scienza di Torino, Turin, Italy (O.R.); Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Moldova (N.R.); Radiological and Medical Sciences Research Institute, Ghana Atomic Energy Commission, Accra, Ghana (I.S.); University Hospital, Lomonosov Moscow State University, Moscow, Russian Federation (V.S.); University Hospital Osijek, Faculty of Medicine, J.J. Strossmayer University of Osijek, Osijek, Croatia (T.T.); and Department of Radiology, Hôpital Européen Georges Pompidou, Paris, France (C.V.N.T.).

出版信息

Radiology. 2021 Mar;298(3):E141-E151. doi: 10.1148/radiol.2020203453. Epub 2020 Nov 10.

Abstract

Background There is lack of guidance on specific CT protocols for imaging patients with coronavirus disease 2019 (COVID-19) pneumonia. Purpose To assess international variations in CT utilization, protocols, and radiation doses in patients with COVID-19 pneumonia. Materials and Methods In this retrospective data collection study, the International Atomic Energy Agency coordinated a survey between May and July 2020 regarding CT utilization, protocols, and radiation doses from 62 health care sites in 34 countries across five continents for CT examinations performed in patients with COVID-19 pneumonia. The questionnaire obtained information on local prevalence, method of diagnosis, most frequent imaging, indications for CT, and specific policies on use of CT in COVID-19 pneumonia. Collected data included general information (patient age, weight, clinical indication), CT equipment (CT make and model, year of installation, number of detector rows), scan protocols (body region, scan phases, tube current and potential), and radiation dose descriptors (CT dose index and dose length product). Descriptive statistics and generalized estimating equations were performed. Results Data from 782 patients (median age, 59 years [interquartile range, 15 years]) from 54 health care sites in 28 countries were evaluated. Less than one-half of the health care sites used CT for initial diagnosis of COVID-19 pneumonia and three-fourths used CT for assessing disease severity. CT dose index varied based on CT vendors (7-11 mGy; < .001), number of detector rows (8-9 mGy; < .001), year of CT installation (7-10 mGy; = .006), and reconstruction techniques (7-10 mGy; = .03). Multiphase chest CT examinations performed at 20% of sites (11 of 54) were associated with higher dose length product compared with single-phase chest CT examinations performed in 80% of sites (43 of 54) ( = .008). Conclusion CT use, scan protocols, and radiation doses in patients with coronavirus disease 2019 pneumonia showed wide variation across health care sites within the same and between different countries. Many patients were imaged multiple times and/or with multiphase CT scan protocols. © RSNA, 2021 See also the editorial by Lee in this issue.

摘要

背景

目前针对 2019 冠状病毒病(COVID-19)肺炎患者的影像学检查,缺乏具体 CT 方案的指导。

目的

评估 COVID-19 肺炎患者 CT 应用、方案和辐射剂量的国际差异。

材料与方法

在这项回顾性数据采集研究中,国际原子能机构于 2020 年 5 月至 7 月协调了一项调查,涉及来自 5 大洲 34 个国家的 62 个医疗保健场所,内容为针对 COVID-19 肺炎患者进行的 CT 检查的 CT 应用、方案和辐射剂量。调查问卷获取了关于当地流行情况、诊断方法、最常见的影像学检查、CT 检查适应证以及 COVID-19 肺炎 CT 应用特定政策的信息。收集的数据包括一般信息(患者年龄、体重、临床适应证)、CT 设备(CT 制造商和型号、安装年份、探测器排数)、扫描方案(身体部位、扫描期、管电流和管电压)和辐射剂量指标(CT 剂量指数和剂量长度乘积)。采用描述性统计和广义估计方程进行分析。

结果

共评估了来自 28 个国家的 54 个医疗保健场所的 782 例患者(中位年龄,59 岁 [四分位距,15 岁])的数据。不到一半的医疗保健场所使用 CT 进行 COVID-19 肺炎的初始诊断,而四分之三的医疗保健场所使用 CT 评估疾病严重程度。根据 CT 供应商(7-11 mGy; <.001)、探测器排数(8-9 mGy; <.001)、CT 安装年份(7-10 mGy; =.006)和重建技术(7-10 mGy; =.03),CT 剂量指数存在差异。20%(11/54)的场所进行的多期胸部 CT 检查与 80%(43/54)的场所进行的单期胸部 CT 检查相比,剂量长度乘积更高( =.008)。

结论

COVID-19 肺炎患者的 CT 应用、扫描方案和辐射剂量在同一国家和不同国家的医疗保健场所之间存在广泛差异。许多患者多次进行影像学检查和/或采用多期 CT 扫描方案。

© 2021 RSNA

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3d4/7673104/6ad465aab727/radiol.2020203453.fig1.jpg

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