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本文引用的文献

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PHAGE Study: Effects of Supplemental Bacteriophage Intake on Inflammation and Gut Microbiota in Healthy Adults.噬菌体研究：补充噬菌体摄入对健康成年人炎症和肠道微生物群的影响。
Nutrients. 2019 Mar 20;11(3):666. doi: 10.3390/nu11030666.
2
Application of Bacteriophages in the Agro-Food Sector: A Long Way Toward Approval.噬菌体在农业食品领域的应用：通向获批之路漫长。
Front Cell Infect Microbiol. 2018 Aug 22;8:296. doi: 10.3389/fcimb.2018.00296. eCollection 2018.
3
Bacteriophage for Gastrointestinal Health (PHAGE) Study: Evaluating the Safety and Tolerability of Supplemental Bacteriophage Consumption.肠道健康噬菌体（PHAGE）研究：评估补充噬菌体摄入的安全性和耐受性。
J Am Coll Nutr. 2019 Jan;38(1):68-75. doi: 10.1080/07315724.2018.1483783. Epub 2018 Aug 29.
4
Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics.噬菌体-吞噬细胞相互作用及其对噬菌体作为治疗剂应用的影响。
Viruses. 2017 Jun 14;9(6):150. doi: 10.3390/v9060150.
5
The human intestinal microbiota of constipated-predominant irritable bowel syndrome patients exhibits anti-inflammatory properties.便秘型肠易激综合征患者的人类肠道微生物群具有抗炎特性。
Sci Rep. 2016 Dec 16;6:39399. doi: 10.1038/srep39399.
6
Microbiome and its impact on gastrointestinal atopy.微生物群及其对胃肠道特应性的影响。
Allergy. 2016 Sep;71(9):1256-63. doi: 10.1111/all.12943. Epub 2016 Jun 23.
7
Overview: Global and Local Impact of Antibiotic Resistance.概述：抗生素耐药性的全球及局部影响
Infect Dis Clin North Am. 2016 Jun;30(2):313-322. doi: 10.1016/j.idc.2016.02.001.
8
Bacteriophage therapy: a regulatory perspective.噬菌体疗法：监管视角
J Antimicrob Chemother. 2016 Aug;71(8):2071-4. doi: 10.1093/jac/dkw083. Epub 2016 Apr 10.
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Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances.抗生素与人类肠道微生物群：生态失调与耐药性积累
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Fecal microbiota transplantation broadening its application beyond intestinal disorders.粪便微生物群移植的应用范围正在扩大，不再局限于肠道疾病。
World J Gastroenterol. 2015 Jan 7;21(1):102-11. doi: 10.3748/wjg.v21.i1.102.

天然来源的食品补充剂中的噬菌体。

Bacteriophages in food supplements obtained from natural sources.

机构信息

Allama Iqbal Open University, Islamabad, Pakistan; MAGI EUREGIO, Bolzano, Italy.

MAGI EUREGIO, Bolzano, Italy.

出版信息

Acta Biomed. 2020 Nov 9;91(13-S):e2020025. doi: 10.23750/abm.v91i13-S.10834.

DOI:10.23750/abm.v91i13-S.10834
PMID:33170168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8023131/
Abstract

Human gastrointestinal tract is colonized by bacteria that constitute the interstinal microbiota. Changes in the microbiota may lead to several chronic disorders. Bacteriophages are viruses that specifically target bacteria. Several food components contain bacteriophages and probiotics. Bacteriophages have a great specificity for harmful bacteria, helping the growth of good bacteria. Because of their qualities, bacteriophages are considered beneficial component of probiotics that target the pathogenic bacteria and support the natural human microbiota.

摘要

人类胃肠道定植着构成肠道微生物群的细菌。微生物群的变化可能导致几种慢性疾病。噬菌体是专门针对细菌的病毒。一些食物成分含有噬菌体和益生菌。噬菌体对有害细菌具有很强的特异性，有助于有益细菌的生长。由于它们的特性，噬菌体被认为是益生菌的有益成分，益生菌靶向致病菌并支持天然人类微生物群。