揭示抗病毒免疫的古老起源。
Unearthing the Ancient Origins of Antiviral Immunity.
机构信息
Institute of Ecology and Evolution, University of Oregon, Eugene, OR 97403, USA.
Institute of Ecology and Evolution, University of Oregon, Eugene, OR 97403, USA; Department of Biology, University of Oregon, Eugene, OR 97403, USA.
出版信息
Cell Host Microbe. 2020 Nov 11;28(5):629-631. doi: 10.1016/j.chom.2020.10.008.
The human genome encodes an arsenal of proteins that protect us against deadly viruses. Could microbes provide clues regarding the origin of these pathogen defenses? In a recent study published in Nature, Bernheim et al. demonstrate that the mammalian antiviral protein viperin is far more ancient and conserved than previously appreciated.
人类基因组编码了一系列的蛋白质，可以保护我们免受致命病毒的侵害。微生物能否为这些病原体防御的起源提供线索呢？在最近发表在《自然》杂志上的一项研究中，Bernheim 等人证明，哺乳动物抗病毒蛋白 viperin 比之前认为的要古老和保守得多。
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