Opt Express. 2020 Nov 9;28(23):34255-34265. doi: 10.1364/OE.401708.
A custom fibre laser designed as an excitation source for biomedical photoacoustic tomography has been developed. It is based on a custom-drawn large core diameter fibre (200 µm) that enables high pulse energies (∼10 mJ) to be achieved. The system can provide variable pulse durations (10 - 500 ns) and pulse repetition frequencies (100 Hz - 1 kHz), as well as arbitrary pulse bursts according to specific user defined sequences. The system is also compact and does not require external water cooling. This, along with the flexibility in the temporal characteristics of its output that it offers, will aid the translation of photoacoustic imaging to practical application in medicine and biology.
已经开发出一种定制的光纤激光作为生物医学光声断层扫描的激发源。它基于一种定制的大芯径光纤（200μm），可以实现高脉冲能量（约 10mJ）。该系统可以提供可变的脉冲持续时间（10-500ns）和脉冲重复频率（100Hz-1kHz），以及根据特定用户定义的序列进行任意脉冲突发。该系统还具有紧凑的结构，不需要外部水冷。这一点，以及它提供的输出时间特性的灵活性，将有助于光声成像在医学和生物学中的实际应用。
