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咪达唑仑:一种用于静脉镇静的新药。

Midazolam: a new drug for intravenous sedation.

作者信息

Midtling J I

出版信息

Anesth Prog. 1987 May-Jun;34(3):87-9.

Abstract

MIDAZOLAM IS SUPERIOR TO DIAZEPAM IN CERTAIN WAYS

it has a more rapid onset; produces greater anterograde amnesia, less postoperative drowsiness, less venous irritation and less likelihood of thrombophlebitis development. However, additional clinical trials may be necessary before it can replace the widely used diazepam.

摘要

咪达唑仑在某些方面优于地西泮

它起效更快;能产生更强的顺行性遗忘、术后嗜睡更少、静脉刺激更小且发生血栓性静脉炎的可能性更低。然而,在它能够取代广泛使用的地西泮之前,可能还需要进行更多的临床试验。

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本文引用的文献

1
Respiratory depression by midazolam and diazepam.
Anesthesiology. 1980 Dec;53(6):494-7. doi: 10.1097/00000542-198012000-00010.
2
Midazolam: a water-soluble benzodiazepine. Studies in volunteers.
Anaesthesia. 1980 May;35(5):454-8. doi: 10.1111/j.1365-2044.1980.tb03821.x.
6
Midazolam as an intravenous induction agent for general anaesthesia: a clinical trial.
Anaesth Intensive Care. 1982 Feb;10(1):29-35. doi: 10.1177/0310057X8201000107.
8

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