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阿尔茨海默病中的维生素——最新报告综述。

Vitamins in Alzheimer's Disease-Review of the Latest Reports.

机构信息

Department of Bromatology, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Mickiewicza 2D Street, 15-222 Białystok, Poland.

出版信息

Nutrients. 2020 Nov 11;12(11):3458. doi: 10.3390/nu12113458.

DOI:10.3390/nu12113458
PMID:33187212
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7696081/
Abstract

Alzheimer's disease (AD) is the most common form of dementia, and the aging of the population means that the number of cases is successively increasing. The cause of the disease has not been established, but it is suggested that many factors affect it, including nutritional aspects. As part of the work, the PubMed database has been searched, beginning from 2005, for terms related to key nutritional aspects. A diet rich in antioxidant vitamins can improve the cognitive functions of patients. Thanks to an adequate intake of B vitamins, homocysteine levels are reduced, which indirectly protects against the development of the disease. A properly balanced diet, as well as the use of appropriate supplementation, can contribute to improving the clinical condition of patients with AD.

摘要

阿尔茨海默病(AD)是最常见的痴呆症形式,随着人口老龄化,病例数量也在相继增加。该病的病因尚未确定,但有研究表明,许多因素都会对其产生影响,包括营养方面。作为工作的一部分,自 2005 年以来,我们已经在 PubMed 数据库中搜索了与关键营养方面相关的术语。富含抗氧化维生素的饮食可以改善患者的认知功能。由于摄入足够的 B 族维生素,同型半胱氨酸水平降低,这间接起到了预防疾病发展的作用。适当的均衡饮食以及适当的补充剂的使用都有助于改善 AD 患者的临床状况。

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本文引用的文献

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Dietary interventions and cognition: A systematic review of clinical trials.膳食干预与认知:临床试验的系统评价。
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The Effect of Adherence to the Mediterranean Diet on Late-Life Cognitive Disorders: A Systematic Review.《坚持地中海饮食对晚年认知障碍的影响:系统评价》。
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Dietary interventions and cognition of Alzheimer's disease patients: a systematic review of randomized controlled trial.饮食干预与阿尔茨海默病患者的认知:一项随机对照试验的系统评价
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Vitamin A and Retinoic Acid in Cognition and Cognitive Disease.维生素 A 和视黄酸在认知和认知疾病中的作用。
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Vitamin B12, B6, or Folate and Cognitive Function in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis.维生素 B12、B6 或叶酸与社区老年人认知功能的关系:系统评价和荟萃分析。
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