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小儿非典型Gradenigo综合征病例:神经影像学的批判性综述

Atypical Gradenigo's syndrome in a pediatric case: A critical review of neuroimaging.

作者信息

Kim Chae-Young, Lee Min Young, Jung Jae Yun, Choi Ji Eun

机构信息

Department of Otolaryngology Head and Neck Surgery, Dankook University Hospital, College of Medicine, Dankook University, Cheonan, South Korea.

出版信息

Radiol Case Rep. 2024 Apr 13;19(7):2633-2638. doi: 10.1016/j.radcr.2024.03.037. eCollection 2024 Jul.

DOI:10.1016/j.radcr.2024.03.037
PMID:38645945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11026535/
Abstract

Gradenigo's syndrome, a rare but serious complication of otitis media, encompasses a triad of symptoms including otalgia, facial palsy, and abducens nerve palsy, pointing to the involvement of the petrous apex. This case report presents an 11-year-old boy with an atypical manifestation of Gradenigo's syndrome, characterized by the absence of classic features such as abducens nerve palsy and purulent otorrhea. MRI findings were significant for petrous apicitis extending to Meckel's cave and the cavernous sinus, along with abscess formation and clivus osteomyelitis. The report highlights the critical role of advanced neuroimaging, particularly MRI, in the diagnosis and management of this condition. It underscores the importance of recognizing atypical presentations of Gradenigo's syndrome and the effectiveness of imaging-guided conservative treatment strategies in pediatric otological cases.

摘要

Gradenigo综合征是中耳炎一种罕见但严重的并发症,包括耳痛、面瘫和展神经麻痹三联征,提示岩尖受累。本病例报告介绍了一名11岁男孩,其表现为Gradenigo综合征的非典型症状,特点是缺乏展神经麻痹和脓性耳漏等典型特征。磁共振成像(MRI)检查结果显示,岩尖炎延伸至梅克尔腔和海绵窦,伴有脓肿形成和斜坡骨髓炎。该报告强调了先进的神经影像学检查,尤其是MRI,在该病诊断和治疗中的关键作用。它强调了认识Gradenigo综合征非典型表现的重要性,以及影像引导下保守治疗策略在儿童耳科病例中的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/a2b04cef449d/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/7e5c73df0ff5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/40668108f865/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/45a196b5a8bd/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/31a34402c0c9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/a2b04cef449d/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/7e5c73df0ff5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/40668108f865/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/45a196b5a8bd/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/31a34402c0c9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f39/11026535/a2b04cef449d/gr5.jpg

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本文引用的文献

1
Petrous apex pneumatisation in children: a radiological study.儿童岩尖气化:一项放射学研究。
J Laryngol Otol. 2020 Aug 24:1-6. doi: 10.1017/S0022215120001681.
2
How well do we know Gradenigo? A comprehensive literature review and proposal for novel diagnostic categories of Gradenigo's syndrome.我们对 Gradenigo 综合征了解多少?一项全面的文献回顾及 Gradenigo 综合征新诊断类别的建议。
Int J Pediatr Otorhinolaryngol. 2020 May;132:109942. doi: 10.1016/j.ijporl.2020.109942. Epub 2020 Feb 8.
3
Brain Abscess Showing a Lack of Restricted Diffusion and Successfully Treated with Linezolid.
脑脓肿表现为扩散不受限并成功接受利奈唑胺治疗。
Brain Tumor Res Treat. 2018 Oct;6(2):92-96. doi: 10.14791/btrt.2018.6.e16.
4
Mastoiditis and Gradenigo's Syndrome with anaerobic bacteria.伴有厌氧菌的乳突炎和Gradenigo综合征。
BMC Ear Nose Throat Disord. 2012 Sep 14;12:10. doi: 10.1186/1472-6815-12-10.