美里克斯SUDS弓形虫检测试验评估
Evaluation of MUREX SUDS Toxo test.
作者信息
Moyer N P, Hudson J D, Hausler W J
机构信息
Hygienic Laboratory, University of Iowa, Iowa City 52242.
出版信息
J Clin Microbiol. 1987 Nov;25(11):2049-53. doi: 10.1128/jcm.25.11.2049-2053.1987.
The SUDS Toxo test (MUREX Corp., Norcross, Ga.) was compared with the indirect hemagglutination test (IHA) and the indirect fluorescent-antibody test (IFA) by examining 404 serum specimens, including 64 (15.8%) specimens with IFA titers of greater than or equal to 1:2. When SUDS was compared with IHA, sensitivity (96.4%), specificity (97.9%), and negative predictive value (99.4%) indicated that there were similar reactivities between the two tests. When an IFA titer of greater than or equal to 1:16 was considered significant and IHA and SUDS were compared with IFA, IHA was slightly less sensitive but had a higher positive predictive value than did SUDS; however, there was no statistical difference between the tests. When SUDS was compared with IFA, in which a titer of greater than or equal to 1:16 was considered significant, the high negative predictive value (100%), excellent sensitivity (100%) and specificity (98.3%), and ease of performance made SUDS an attractive alternative to IHA for screening single serum specimens for toxoplasmosis.
通过检测404份血清标本（其中64份（15.8%）间接荧光抗体试验（IFA）效价大于或等于1:2），将SUDS弓形虫检测试验（MUREX公司，佐治亚州诺克罗斯）与间接血凝试验（IHA）和间接荧光抗体试验（IFA）进行比较。当将SUDS与IHA比较时，敏感性（96.4%）、特异性（97.9%）和阴性预测值（99.4%）表明这两种试验之间存在相似的反应性。当将效价大于或等于1:16的IFA视为有意义，并将IHA和SUDS与IFA进行比较时，IHA的敏感性略低，但阳性预测值高于SUDS；然而，这些试验之间没有统计学差异。当将SUDS与效价大于或等于1:16视为有意义的IFA进行比较时，SUDS的高阴性预测值（100%）、出色的敏感性（100%）和特异性（98.3%）以及操作简便，使其成为用于筛查单个血清标本弓形虫病的IHA的有吸引力的替代方法。
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