Tameez Ud Din Asim, Alam Faran, Tameez-Ud-Din Ahsan, Chaudhary Farooq Mohyud Din
Internal Medicine, Shifa International Hospital, Islamabad, PAK.
Internal Medicine, Rawalpindi Medical University, Rawalpindi, PAK.
Cureus. 2020 Oct 16;12(10):e10983. doi: 10.7759/cureus.10983.
Auto-brewery syndrome (ABS), also known as gut fermentation syndrome, is a very rare disorder. It is characterized by the endogenous production of alcohol. It typically presents with the signs of alcohol intoxication, such as staggering gait, slurred speech, gastrointestinal distress, and state of confusion. Due to the nonspecific symptoms, it is necessary to rule out other etiologies before reaching a diagnosis of ABS. The confirmatory test for this syndrome is the raised levels of blood or breath ethanol after a glucose challenge test. The management includes the use of antifungal drugs and avoidance of a carbohydrate-rich diet. In this review, we summarize the etiology, clinical presentation, diagnostic tests, management, and medicolegal aspects of ABS.
自动酿酒综合征（ABS），也称为肠道发酵综合征，是一种非常罕见的疾病。其特征是内源性酒精生成。它通常表现出酒精中毒的症状，如步态蹒跚、言语含糊、胃肠道不适和意识混乱状态。由于症状不具特异性，在诊断自动酿酒综合征之前有必要排除其他病因。该综合征的确证试验是葡萄糖激发试验后血液或呼气中乙醇水平升高。治疗包括使用抗真菌药物和避免高碳水化合物饮食。在本综述中，我们总结了自动酿酒综合征的病因、临床表现、诊断测试、治疗及法医学方面的内容。
