Patel Priyansh, Patel Diya, Gutlapalli Sai Dheeraj, Okorie Ikpechukwu J, Onana Arnold E, Ugwendum Derek, Arrey Agbor Divine Besong, Munoh Kenne Foma, Otterbeck Philip, Nfonoyim Jay
Department of Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Department of Internal Medicine, Baroda Medical College, Vadodara, IND.
Cureus. 2023 Jul 15;15(7):e41924. doi: 10.7759/cureus.41924. eCollection 2023 Jul.
Endogenous production of alcohol without the external intake of alcohol is called auto-brewery syndrome (ABS), and to get its levels to rise to a level that it has physical symptoms of alcohol intake is rare. The most common cause of ABS is the metabolism of ingested carbohydrates by intestinal microflora. This occurrence does not happen in all normal individuals but only in some high-risk individuals. Patients with diabetes mellitus (DM) have been hypothesized to be at high risk for ABS. We searched databases, such as PubMed, Medline, and PubMed Central, to search for existing literature with relevant keywords. In the finalized review, we have included 30 relevant articles. Alcohol formed in the gut gets absorbed in the bloodstream and immediately gets metabolized, so usually it does not achieve a level in blood high enough to cause symptoms. In high-risk patients, there is an increase in the level of bloodstream alcohol above a certain level, so it shows symptoms. Because there is higher blood glucose in DM, the patients have been shown to be at increased risk for developing ABS. Similarly, obesity is also a risk factor for DM, making it a high-risk condition for ABS. The most involved pathogens are and .
在没有外部摄入酒精的情况下内源性产生酒精被称为自动酿酒综合征（ABS），而使其水平升高到出现酒精摄入身体症状的情况很少见。ABS最常见的原因是肠道微生物群对摄入碳水化合物的代谢。这种情况并非在所有正常个体中都会发生，而仅在一些高危个体中出现。糖尿病（DM）患者被认为是患ABS的高危人群。我们检索了诸如PubMed、Medline和PubMed Central等数据库，以搜索带有相关关键词的现有文献。在最终的综述中，我们纳入了30篇相关文章。在肠道中形成的酒精会被血液吸收并立即代谢，所以通常它在血液中不会达到足以引起症状的水平。在高危患者中，血液中酒精水平会升高到一定程度以上，从而出现症状。由于DM患者血糖较高，已表明他们患ABS的风险增加。同样，肥胖也是DM的一个风险因素，使其成为患ABS的高危情况。最常见的致病病原体是 和 。 （原文此处缺失具体病原体名称）
