Cologne Merheim Hospital, Department of Thoracic Surgery, Kliniken der Stadt Köln gGmbH, Witten/Herdecke University, Cologne, Germany.
Cologne Merheim Hospital, Department of Pneumology, Kliniken der Stadt Köln gGmbH, Witten/Herdecke University, Cologne, Germany.
Interact Cardiovasc Thorac Surg. 2021 Jan 22;32(2):244-249. doi: 10.1093/icvts/ivaa258.
Measurement tools of health-related quality of life (HRQL) that are specific for the underlying disorder are inevitably needed to assess HRQL changes following specific treatment strategies. The aim of the current study was to develop a questionnaire assessing HRQL in patients with unilateral diaphragmatic paresis.
Firstly, topics of health impairments covering physical, psychological, social and functional aspects were predefined by a physician expert panel to ensure face validity. Secondly, all predefined topics were rated by a patient group with unilateral diaphragmatic paresis (untreated: n = 11; postoperative: n = 9) using a 5-point Likert scale ranging from 'not relevant at all' (-2) to 'absolutely relevant' (+2) to guarantee content validity. Thirdly, only relevant topics (0 to +2) were used for item development, while non-relevant items (<0) were not subject for item development.
In total, 20 patients rated a total of 43 topics covering a broad spectrum of health impairment. 21 were considered as relevant for item development. Items are answered on a 5-point Likert scale ranging from 'completely untrue' (-2) to 'always true' (+2). The Diaphragmatic Paralysis Questionnaire (DPQ) Summary Score ranges from 0 (worst HRQL) to 100 (best HRQL). Finally, the German DPQ was professionally translated and transculturally adapted into English, Italian, Dutch, French, Greek and Spanish, using translation/back-translation procedures.
The DPQ is the first diseases-specific HRQL measure developed for patients with diaphragmatic paresis. In addition, the DPQ is available in 7 languages free of charge for non-profit purposes.
German clinical trials register: DRKS00017056.
评估特定治疗策略后健康相关生活质量（HRQL）的变化，不可避免地需要使用针对潜在疾病的 HRQL 测量工具。本研究的目的是开发一种评估单侧膈肌麻痹患者 HRQL 的问卷。
首先，由医生专家小组预先确定涵盖身体、心理、社会和功能方面的健康损害主题，以确保表面效度。其次，所有预先确定的主题均由单侧膈肌麻痹患者组（未治疗：n=11；术后：n=9）使用 5 点 Likert 量表进行评分，范围从“完全不相关”（-2）到“绝对相关”（+2），以保证内容效度。第三，仅使用相关主题（0 到+2）进行项目开发，而不相关项目（<0）不进行项目开发。
共有 20 名患者对共 43 个涵盖广泛健康损害的主题进行了评分。其中 21 个被认为与项目开发相关。项目采用 5 点 Likert 量表进行评分，范围从“完全不真实”（-2）到“总是真实”（+2）。膈肌麻痹问卷（DPQ）总分范围为 0（最差 HRQL）至 100（最佳 HRQL）。最后，德语 DPQ 经过专业翻译和跨文化适应，被翻译成英语、意大利语、荷兰语、法语、希腊语和西班牙语，使用翻译/回译程序。
DPQ 是为膈肌麻痹患者开发的第一个针对特定疾病的 HRQL 测量工具。此外，DPQ 可免费用于非盈利目的的 7 种语言。
德国临床试验注册处：DRKS00017056。
