Department of Chemical Sciences, Tai Solarin University of Education, Ijebu Ode, Ogun State, Nigeria.
Department of Chemistry, University of Ibadan, Ibadan, Nigeria.
Nat Prod Res. 2022 Apr;36(8):2154-2157. doi: 10.1080/14786419.2020.1844691. Epub 2020 Nov 23.
is an annual herb which has tremendous medicinal uses. The antioxidant activity of the whole plant extract of was investigated using DPPH radical scavenging activity. Purified compounds were isolated using column chromatography method. Their structures were determined using various spectroscopic techniques. A new compound named as Squalen-1-ol, Phytol, squalene and α-tocopherol were isolated. These compounds were isolated for the first time from The extract of gave a significant IC value of 0.77 mg/mL as compared with the standard ascorbic acid with IC value of 0.24 mg/mL. It can be correlated that the antioxidant activity of could be attributed to the presence of α - tocopherol which is a known antioxidant. The presence of these compounds gives a further added pharmacological value to the plant.
是一种一年生草本植物，具有巨大的药用价值。使用 DPPH 自由基清除活性研究了全植物提取物的抗氧化活性。使用柱色谱法分离纯化化合物。使用各种光谱技术确定其结构。分离得到一种新化合物角鲨烯-1-醇、植醇、角鲨烯和α-生育酚。这些化合物是首次从 中分离得到的。与 IC 值为 0.24 mg/mL 的标准抗坏血酸相比， 提取物的 IC 值为 0.77 mg/mL。可以推断， 的抗氧化活性可能归因于存在已知抗氧化剂的 α - 生育酚。这些化合物的存在使该植物具有进一步的药理价值。
