Ustaoğlu Gülbahar, Erdal Emrah
Dentistry Faculty, Department of Periodontology, Bolu Abant İzzet Baysal University, 14300, Bolu, Turkey.
Medical Faculty, Department of Cardiology, Bolu Abant İzzet Baysal University, Bolu, Turkey.
Int J Implant Dent. 2020 Nov 25;6(1):73. doi: 10.1186/s40729-020-00273-z.
The aim of this paper is to explore the serum biochemical parameters also known as risk markers for cardiovascular system, in individuals who have received dental implant treatment, and to reveal risk factors for peri-implant diseases.
The study included 58 subjects with peri-implantitis, 49 subjects with peri-implant mucositis, and 49 healthy subjects. All the subjects were assessed in terms of both peri-implant clinical parameters-probing depth (PD), bleeding on probing (BOP), the type of prosthesis, gingival index (GI), keratinized mucosa width (KMW), and plaque index (PI)-and serum biochemical parameters (e.g., LDL cholesterol, HDL cholesterol, triglyceride, total cholesterol, vitamin D, uric acid, white blood cell (WBC), neutrophil, hemoglobin (Hb), and platelet counts).
KMW was the lowest in the peri-implantitis group. Compared with the other groups, the peri-implantitis group showed significantly higher levels of triglyceride, uric acid, and WBC. The peri-implantitis group had the lowest level of vitamin D. Triglyceride and uric acid levels had positive correlations with peri-implant clinical parameters.
High levels of triglyceride and uric acid may pose a risk for both peri-implant diseases and cardiovascular diseases. Prior to dental implant surgery, patients' serum biochemical parameters should be checked.
本文旨在探究接受牙种植治疗的个体中也被称为心血管系统风险标志物的血清生化参数，并揭示种植体周围疾病的危险因素。
该研究纳入了58例种植体周围炎患者、49例种植体周围黏膜炎患者和49例健康受试者。所有受试者均接受了种植体周围临床参数（探诊深度（PD）、探诊出血（BOP）、修复体类型、牙龈指数（GI）、角化黏膜宽度（KMW）和菌斑指数（PI））以及血清生化参数（如低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、甘油三酯、总胆固醇、维生素D、尿酸、白细胞（WBC）、中性粒细胞、血红蛋白（Hb）和血小板计数）的评估。
种植体周围炎组的KMW最低。与其他组相比，种植体周围炎组的甘油三酯、尿酸和WBC水平显著更高。种植体周围炎组的维生素D水平最低。甘油三酯和尿酸水平与种植体周围临床参数呈正相关。
高甘油三酯和尿酸水平可能对种植体周围疾病和心血管疾病均构成风险。在进行牙种植手术前，应检查患者的血清生化参数。
