Department of Pharmaceutics and Food Technology, Faculty of Pharmacy, Complutense University of Madrid, 28040 Madrid, Spain.
Mar Drugs. 2020 Nov 23;18(11):583. doi: 10.3390/md18110583.
Marine resources are today a renewable source of various compounds, such as polysaccharides, that are used in the pharmaceutical, medical, cosmetic, and food fields. In recent years, considerable attention has been focused on carrageenan-based biomaterials due to their multifunctional qualities, including biodegradability, biocompatibility, and non-toxicity, in addition to bioactive attributes, such as their antiviral, antibacterial, antihyperlipidemic, anticoagulant, antioxidant, antitumor, and immunomodulating properties. They have been applied in pharmaceutical formulations as both their bioactive and physicochemical properties make them suitable biomaterials for drug delivery, and recently for the development of tissue engineering. This article provides a review of recent research on the various types of carrageenan-based biomedical and pharmaceutical applications.
海洋资源是各种化合物的可再生来源，如多糖，这些化合物被用于制药、医学、化妆品和食品领域。近年来，由于其多功能特性，包括生物降解性、生物相容性和无毒，以及抗病毒、抗菌、抗高血脂、抗凝、抗氧化、抗肿瘤和免疫调节等生物活性特性，基于角叉菜胶的生物材料受到了极大的关注。它们已被应用于药物制剂中，因为它们的生物活性和物理化学性质使它们成为适合药物输送的生物材料，最近还用于组织工程的开发。本文综述了近年来基于角叉菜胶的生物医学和药物应用的各种类型的研究。
