Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Department of Ophthalmology, University Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Eye (Lond). 2021 Jan;35(1):17-32. doi: 10.1038/s41433-020-01288-x. Epub 2020 Nov 25.
Optical coherence tomography (OCT) is a non-invasive medical imaging technology that is playing an increasing role in the routine assessment and management of patients with neuro-ophthalmic conditions. Its ability to characterise the optic nerve head, peripapillary retinal nerve fibre layer and cellular layers of the macula including the ganglion cell layer enables qualitative and quantitative assessment of optic nerve disease. In this review, we discuss technical features of OCT and OCT-based imaging techniques in the neuro-ophthalmic context, potential pitfalls to be aware of, and specific applications in more common neuro-ophthalmic conditions including demyelinating, inflammatory, ischaemic and compressive optic neuropathies, optic disc drusen and raised intracranial pressure. We also review emerging applications of OCT angiography within neuro-ophthalmology.
光学相干断层扫描（OCT）是一种非侵入性的医学成像技术，在神经眼科疾病患者的常规评估和管理中发挥着越来越重要的作用。它能够对视盘、视盘周围视网膜神经纤维层和黄斑区的细胞层，包括神经节细胞层进行定性和定量评估，从而对视神经疾病进行评估。在本文中，我们讨论了神经眼科领域 OCT 及其基于 OCT 的成像技术的技术特点、需要注意的潜在陷阱以及在常见神经眼科疾病中的特定应用，包括脱髓鞘、炎症、缺血和压迫性视神经病变、视盘玻璃疣和颅内压升高。我们还回顾了 OCT 血管造影在神经眼科领域的新兴应用。
