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抗菌肽组合对肉鸡生长性能、肠道健康和免疫功能的影响。

Effects of antibacterial peptide combinations on growth performance, intestinal health, and immune function of broiler chickens.

机构信息

College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, 510642 P. R. China; Ministry of Agriculture Key Laboratory of Tropical Agricultural Environment, South China Agricultural University, Guangzhou, 510642 P. R. China; Guangdong Engineering Research Center for Vector Vaccine of Animal Virus, Guangzhou, 510642 P. R. China.

Guangdong Laboratory of Lingnan Modern Agriculture, Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou, 510642 P. R. China; Guangdong Engineering Research Center for Vector Vaccine of Animal Virus, Guangzhou, 510642 P. R. China.

出版信息

Poult Sci. 2020 Dec;99(12):6481-6492. doi: 10.1016/j.psj.2020.08.068. Epub 2020 Sep 14.

DOI:10.1016/j.psj.2020.08.068
PMID:33248563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7810918/
Abstract

To study the effects of antibacterial peptides (ABPs) on feeding broilers, this experiment compared the 2 combinations of ABP with antibiotics by separately adding the supplement to the diet of 818 broilers as follows-antibiotics, Pratt and Full-tide, and Pratt and plant essential oil-and then the effect of them on production performance, immune function, antioxidant capacity, serum biochemical indicators, and microorganisms of the experimental flocks was investigated and compared. It was found that the aforementioned indicators among the 2 groups of ABP and the antibiotic group were close to or even better than those of antibiotics, and the combination added with plant essential oils had generally better effects. These results indicated that ABPs could improve economic benefits by promoting growth, preventing disease, and reducing the rate of death. This study deepened the research on the action mechanism of ABPs and not only explored the feasibility of ABPs as a novel feed additive for broilers but also provided experimental data and theoretical basis for the application of ABPs.

摘要

为研究抗菌肽(ABPs)对肉仔鸡的影响,本试验通过在 818 羽肉仔鸡的日粮中分别添加抗生素 Pratt 和 Full-tide、抗生素 Pratt 和植物精油这 2 种 ABPs 组合,与抗生素进行对比,研究比较了它们对试验鸡群生产性能、免疫功能、抗氧化能力、血清生化指标和微生物的影响。结果表明,2 组 ABPs 与抗生素组的上述指标均接近或优于抗生素,且添加植物精油的组合效果普遍更好。这些结果表明,ABPs 可以通过促进生长、预防疾病和降低死亡率来提高经济效益。本研究深化了 ABPs 作用机制的研究,不仅探索了 ABPs 作为新型肉仔鸡饲料添加剂的可行性,还为 ABPs 的应用提供了实验数据和理论基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/4cd9cf5b594a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/bdd8127c5388/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/788f99bb288a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/9da6b83b1397/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/befaa45b72b1/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/4cd9cf5b594a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/bdd8127c5388/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/788f99bb288a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/9da6b83b1397/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/befaa45b72b1/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ab/7810918/4cd9cf5b594a/gr5.jpg

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2
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J Am Dent Assoc. 2018 Oct;149(10):869-884.e5. doi: 10.1016/j.adaj.2018.05.034.
3
Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons.流感病毒通过I型干扰素影响肠道微生物群及肠道中的继发性沙门氏菌感染。
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Front Vet Sci. 2025 Apr 25;12:1550776. doi: 10.3389/fvets.2025.1550776. eCollection 2025.
4
Effects of replacing antibiotics with probiotics and antimicrobial peptides on performance, gut health, carcass traits, meat quality, and welfare in broilers infected with Eimeria and Clostridium perfringens.用益生菌和抗菌肽替代抗生素对感染艾美耳球虫和产气荚膜梭菌的肉鸡生产性能、肠道健康、胴体性状、肉质和福利的影响。
Trop Anim Health Prod. 2025 Apr 24;57(4):184. doi: 10.1007/s11250-025-04441-4.
5
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Probiotics Antimicrob Proteins. 2025 Jan 10. doi: 10.1007/s12602-025-10448-y.
6
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PLoS Pathog. 2016 May 5;12(5):e1005572. doi: 10.1371/journal.ppat.1005572. eCollection 2016 May.
4
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Front Neurosci. 2014 Dec 3;8:392. doi: 10.3389/fnins.2014.00392. eCollection 2014.
5
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6
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Biosci Biotechnol Biochem. 2012;76(2):283-8. doi: 10.1271/bbb.110646. Epub 2012 Feb 7.
7
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Cell Res. 2012 Mar;22(3):528-38. doi: 10.1038/cr.2011.165. Epub 2011 Oct 25.
8
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9
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10
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