来自不同来源的巨噬细胞培养物中鼠麻风分枝杆菌的生长情况。
Growth of Mycobacterium lepraemurium in cultures of macrophages obtained from various sources.
作者信息
Yamagami A, Chang Y T
出版信息
Infect Immun. 1977 Sep;17(3):531-4. doi: 10.1128/iai.17.3.531-534.1977.
Abstract
Studies were made on the growth of Mycobacterium lepraemurium in cultures of macrophages obtained from various sources, such as bone marrow, spleen, and blood of mice. Macrophages were maintained in good condition for more than 12 weeks. Marked intracellular multiplication of M. lepraemurium was observed in cultures from all three sources. Whereas M. lepraemurium freshly prepared from the animals showed good growth in the cultures, those that were kept at 4 degrees C for 10 or 14 days showed no growth.
摘要
对从各种来源（如小鼠的骨髓、脾脏和血液）获取的巨噬细胞培养物中鼠麻风分枝杆菌的生长情况进行了研究。巨噬细胞在良好状态下维持了超过12周。在来自所有这三种来源的培养物中均观察到鼠麻风分枝杆菌明显的细胞内增殖。刚从动物体内制备的鼠麻风分枝杆菌在培养物中生长良好，而那些在4摄氏度下保存10天或14天的则没有生长。
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