对 4082 例中国患者的解脲脲原体和人型支原体的检查。
Examination of Ureaplasma urealyticum and Mycoplasma hominis in 4082 Chinese patients.
机构信息
Division of Life Sciences and Medicine, Department of Clinical Laboratory, First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, China.
School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui, China.
出版信息
Braz J Med Biol Res. 2020 Nov 27;54(2):e10099. doi: 10.1590/1414-431X202010099. eCollection 2020.
The objective of this study was to analyze the infection rate and drug resistance of Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) in the genitourinary tract of Chinese patients. From December 2018 to June 2019, vaginal secretion or urinary secretion of outpatients in our hospital were selected for culture and drug sensitivity analysis of Ureaplasma urealyticum and Mycoplasma hominis. In 4082 Chinese samples, 1567 Mycoplasma were detected, a detection rate of 38.39%, among which 1366 cases were UU single positive, accounting for 33.47%, 15 cases were MH single positive, accounting for 0.36%, 186 cases were UU and MH mixed positive, accounting for 4.56%. The most affected age groups were 21-30 years and 31-40 years, accounting for 19.09 and 15.05%, respectively. The results of drug sensitivity showed that doxycycline, minocycline, josamycin, clarithromycin, and roxithromycin were more sensitive to mycoplasma infection. The distribution of Ureaplasma urealyticum and Mycoplasma hominis in the human genitourinary system and their sensitivity to antibiotics is different for sex and age groups.
本研究旨在分析中国患者泌尿生殖道解脲脲原体（UU）和人型支原体（MH）的感染率及耐药性。2018 年 12 月至 2019 年 6 月，选取我院门诊阴道分泌物或尿分泌物进行解脲脲原体和人型支原体的培养及药敏分析。在 4082 例中国样本中，检测到 1567 例支原体，检出率为 38.39%，其中 UU 单纯阳性 1366 例，占 33.47%，MH 单纯阳性 15 例，占 0.36%，UU 和 MH 混合阳性 186 例，占 4.56%。受影响最严重的年龄组为 21-30 岁和 31-40 岁，分别占 19.09%和 15.05%。药敏结果显示，强力霉素、米诺环素、交沙霉素、克拉霉素和罗红霉素对支原体感染更为敏感。解脲脲原体和人型支原体在人类泌尿生殖系统中的分布及其对抗生素的敏感性因性别和年龄组而异。
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