Engelbrecht Francois A, Scholes Robert J
Global Change Institute, University of the Witwatersrand, South Africa.
Covid-19 Environmental Reference Group, South Africa.
One Health. 2021 Jun;12:100202. doi: 10.1016/j.onehlt.2020.100202. Epub 2020 Nov 29.
Ten months into the Covid-19 pandemic it remains unclear whether transmission of SARS-CoV-2 is affected by climate factors. Using a dynamic epidemiological model with Covid-19 climate sensitivity in the likely range, we demonstrate why attempts to detect a climate signal in Covid-19 have thus far been inconclusive. Then we formulate a novel methodology based on susceptible-infected time trajectories that can be used to test for seasonal climate sensitivity in observed Covid-19 infection data. We show that if the disease have a substantial seasonal dependence, and herd immunity is not established during the first peak season of the outbreak (or a vaccine does not become available), there is likely to be a seasonality-sensitive second wave of infections about one year after the initial outbreak. In regions where non-pharmaceutical control has contained the disease in the first year of outbreak and thus kept a large portion of the population susceptible, the second wave may be substantially larger in amplitude than the first if control measures are relaxed. This is simply because it develops under the favorable conditions of a full autumn to winter period and from a larger pool of infected individuals.
在新冠疫情爆发十个月后,目前仍不清楚严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的传播是否受气候因素影响。我们使用一个动态流行病学模型,该模型对新冠病毒的气候敏感性处于可能的范围内,以此证明为何迄今为止在新冠疫情中检测气候信号的尝试尚无定论。然后,我们基于易感者-感染者时间轨迹制定了一种新颖的方法,可用于检验观察到的新冠病毒感染数据中的季节性气候敏感性。我们表明,如果该疾病存在显著的季节性依赖,且在疫情爆发的首个高峰季节未建立群体免疫(或未获得疫苗),那么在首次爆发约一年后,可能会出现对季节敏感的第二轮感染。在疫情爆发第一年通过非药物控制措施控制住疾病、从而使很大一部分人口仍易感染的地区,如果放松控制措施,第二轮感染的规模可能会比第一轮大得多。这仅仅是因为第二轮感染是在整个秋冬季节的有利条件下,且从更大的感染人群基数中发展而来的。