Scarano Aurelia, Chieppa Marcello, Santino Angelo
Institute of Science of Food Production, C.N.R. Unit of Lecce, 73100 Lecce, Italy.
National Institute of Gastroenterology 'S. De Bellis', Institute of Research, 70013 Castellana Grotte, Italy.
Antioxidants (Basel). 2020 Dec 3;9(12):1225. doi: 10.3390/antiox9121225.
Plant food biofortification is recently receiving remarkable attention, as it aims to increase the intake of minerals, vitamins, or antioxidants, crucial for their contribution to the general human health status and disease prevention. In this context, the study of the plant's secondary metabolites, such as polyphenols, plays a pivotal role for the development of a new generation of plant crops, compensating, at least in part, the low nutritional quality of Western diets with a higher quality of dietary sources. Due to the prevalent immunomodulatory activity at the intestinal level, polyphenols represent a nutritionally relevant class of plant secondary metabolites. In this review, we focus on the antioxidant and anti-inflammatory properties of different classes of polyphenols with a specific attention to their potential in the prevention of intestinal pathological processes. We also discuss the latest biotechnology strategies and new advances of genomic techniques as a helpful tool for polyphenols biofortification and the development of novel, healthy dietary alternatives that can contribute to the prevention of inflammatory bowel diseases.
植物性食物生物强化最近受到了显著关注，因为它旨在增加矿物质、维生素或抗氧化剂的摄入量，这些物质对促进人类总体健康状况和预防疾病至关重要。在此背景下，对植物次生代谢产物（如多酚）的研究对于新一代作物的开发起着关键作用，至少在一定程度上弥补西方饮食中营养质量较低的问题，提供更高质量的膳食来源。由于多酚在肠道水平具有普遍的免疫调节活性，它们代表了一类具有营养相关性的植物次生代谢产物。在这篇综述中，我们重点关注不同类别的多酚的抗氧化和抗炎特性，特别关注它们在预防肠道病理过程中的潜力。我们还讨论了最新的生物技术策略和基因组技术的新进展，这些技术是有助于多酚生物强化以及开发新型健康膳食替代品的有用工具，而这些替代品有助于预防炎症性肠病。
