Department of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran.
Department of Analytical Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran.
Talanta. 2021 Feb 1;223(Pt 1):121411. doi: 10.1016/j.talanta.2020.121411. Epub 2020 Jul 18.
One of the pressing concerns in analytical chemistry is the construction of selective and sensitive sensors to detect trace analytes in complicated samples. Nowadays, molecularly imprinted polymers (MIPs) that play an important role in most sensing systems are created by molecular imprinting technology (MIT) with tailor-made and synthetic recognition sites, which are complementary in functional groups, size, and shape to the target molecule. Fluorescent carbon dots (CDs), as a new class of carbon-based nanomaterials, have shown simple synthesis, low cost, excellent optical features, great aqueous solubility, and good biocompatibility. Due to the unique properties of recognition specificity, structure predictability, and application universality, the coupling of MIP/CDs with fluorescence detection has attracted great research interest. Accordingly, this review article mainly focuses on the senor designs, sensing mechanisms, and properties of MIP/CDs based fluorescent sensors to various target analytes in most recent years. Finally, we discuss possible future challenges, improvements, and perspectives.
分析化学领域的一个紧迫问题是构建选择性和灵敏的传感器，以检测复杂样品中的痕量分析物。如今，在大多数传感系统中发挥重要作用的分子印迹聚合物（MIP）是通过分子印迹技术（MIT）创建的，具有定制和合成的识别位点，这些识别位点在功能基团、大小和形状上与目标分子互补。荧光碳点（CDs）作为一类新型的碳基纳米材料，具有合成简单、成本低、光学性能优异、水溶性好、生物相容性好等特点。由于具有独特的识别特异性、结构可预测性和应用通用性，MIP/CDs 与荧光检测的结合引起了极大的研究兴趣。因此，本文主要综述了近年来基于 MIP/CDs 的荧光传感器对各种目标分析物的传感器设计、传感机制和性能。最后，我们讨论了可能的未来挑战、改进和展望。
