基于基因组数据对哈萨克斯坦两起炭疽疫情之间关系的回顾性分析。
Retrospective Analysis of the Relationship between Two Anthrax Outbreaks in Kazakhstan Based on Genomic Data.
作者信息
Shevtsov Alexandr, Vergnaud Gilles, Amirgazin Asylulan, Lukhnova Larissa, Izbanova Uinkul, Shevtsov Vladislav, Ramankulov Yerlan
机构信息
National Center for Biotechnology, Nur-Sultan, Kazakhstan
Université Paris-Saclay, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
出版信息
Microbiol Resour Announc. 2020 Dec 10;9(50):e01126-20. doi: 10.1128/MRA.01126-20.
We present a retrospective analysis of strains from two anthrax outbreaks in western Kazakhstan in 2009. The outbreaks occurred during the same period and in the same area located close to main roads, favoring a single source of infection. However, multilocus variable-number tandem-repeat analysis (MLVA), canonical single-nucleotide polymorphism (CanSNP) analysis, and genome-wide analysis demonstrated that the outbreaks were not connected.
我们对2009年哈萨克斯坦西部两次炭疽疫情的菌株进行了回顾性分析。两次疫情发生在同一时期，且在靠近主要道路的同一区域，这表明可能存在单一传染源。然而，多位点可变数目串联重复序列分析（MLVA）、典型单核苷酸多态性（CanSNP）分析和全基因组分析表明，这两次疫情并无关联。
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