大麻作用的神经分子机制。
Neuromolecular Mechanisms of Cannabis Action.
机构信息
University of Nottingham. Faculty of Medicine & Health Sciences, Nottingham, UK.
出版信息
Adv Exp Med Biol. 2021;1264:15-28. doi: 10.1007/978-3-030-57369-0_2.
PMID:33332001
Abstract
Most of our current understanding of the neuromolecular mechanisms of Cannabis action focusses on two plant cannabinoids, THC and CBD. THC acts primarily through presynaptic CB cannabinoid receptors to regulate neurotransmitter release in the brain, spinal cord and peripheral nerves. CBD action, on the other hand, is probably mediated through multiple molecular targets.
摘要
我们目前对大麻作用的神经分子机制的大部分理解都集中在两种植物大麻素，即 THC 和 CBD 上。THC 主要通过突触前 CB 大麻素受体来调节大脑、脊髓和外周神经中的神经递质释放。另一方面，CBD 的作用可能是通过多种分子靶标介导的。
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