Faculty of Chemistry and Chemical Engineering, University of Maribor, SI-2000 Maribor, Slovenia.
Faculty of Medicine, University of Maribor, SI-2000 Maribor, Slovenia.
Molecules. 2020 Dec 15;25(24):5946. doi: 10.3390/molecules25245946.
According to many reports, phenolic compounds isolated from olive leaves have very good biological activities, especially antimicrobial. Presently, the resistance of microorganisms to antibiotics is greater than ever. Therefore, there are numerous recent papers about alternative solutions for inhibiting their influence on human health. Olive leaf is studied as an important source of antimicrobials with low cost and used in medicine. Numerous publications on involving green technologies for isolation of active compounds from olive leaves have appeared over the past few decades. The present review reports on current knowledge of the most isolated phenolic compounds from olive leaf extract as well as methods for their isolation and characterization. This paper uses recent research findings with a wide range of study models to describe the antimicrobial potential of phenolic compounds. It also describes the vast range of information about methods for determination of antimicrobial potential focusing on effects on different microbes. Additionally, it serves to highlight the role of olive leaf extract as an antioxidants and presents methods for determination of antioxidant potential. Furthermore, it provides an overview of presence of enzymes. The significance of olive leaves as industrial and agricultural waste is emphasized by means of explaining their availability, therapeutic and nutritional effects, and research conducted on this field.
根据许多报告,从橄榄叶中分离出的酚类化合物具有很好的生物活性,特别是抗菌活性。目前,微生物对抗生素的耐药性比以往任何时候都大。因此,有许多关于抑制它们对人类健康影响的替代解决方案的最新论文。橄榄叶作为一种具有低成本和药用价值的抗菌药物的重要来源而受到研究关注。在过去几十年中,出现了许多关于利用绿色技术从橄榄叶中分离活性化合物的出版物。本综述报告了从橄榄叶提取物中分离出的最常见酚类化合物的最新知识,以及它们的分离和特性鉴定方法。本文利用最近的研究成果和广泛的研究模型,描述了酚类化合物的抗菌潜力。它还描述了大量关于测定抗菌潜力的方法的信息,重点是对不同微生物的影响。此外,它强调了橄榄叶提取物作为抗氧化剂的作用,并介绍了抗氧化潜力的测定方法。此外,它还概述了酶的存在。通过解释橄榄叶在工业和农业废物方面的可用性、治疗和营养作用以及该领域的研究,强调了橄榄叶的重要意义。