Geelong Centre for Emerging Infectious Diseases, Geelong, VIC, 3220, Australia.
School of Medicine, Deakin University, Geelong, VIC, 3220, Australia.
Sci Rep. 2020 Dec 17;10(1):22284. doi: 10.1038/s41598-020-79413-9.
Birds, notably wild ducks, are reservoirs of pathogenic and zoonotic viruses such as influenza viruses and coronaviruses. In the current study, we used metagenomics to detect and characterise avian DNA and RNA viruses from wild Pacific black ducks, Chestnut teals and Grey teals collected at different time points from a single location. We characterised a likely new species of duck aviadenovirus and a novel duck gyrovirus. We also report what, to the best of our knowledge, is the first finding of an avian orthoreovirus from Pacific black ducks and a rotavirus F from Chestnut teals. Other viruses characterised from the samples from these wild ducks belong to the virus families Astroviridae, Caliciviridae and Coronaviridae. Some of the viruses may have potential cross-species transmissibility, while others indicated a wide genetic diversity of duck viruses within a genus. The study also showed evidence of potential transmission of viruses along the East Asian-Australasian Flyway; potentially facilitated by migrating shorebirds. The detection and characterisation of several avian viruses not previously described, and causing asymptomatic but potentially also symptomatic infections suggest the need for more virus surveillance studies for pathogenic and potential zoonotic viruses in wildlife reservoirs.
鸟类，尤其是野生鸭类，是流感病毒和冠状病毒等病原体和人畜共患病病毒的宿主。在本研究中，我们使用宏基因组学技术，从一个地点不同时间采集的野生太平洋黑鸭、栗喉鸭和灰头绿鸭中检测和鉴定了禽 DNA 和 RNA 病毒。我们鉴定了一种可能的新型鸭腺病毒和一种新型鸭回转病毒。我们还报告了据我们所知，首次从太平洋黑鸭中发现的禽正呼肠孤病毒和从栗喉鸭中发现的轮状病毒 F。从这些野生鸭中分离出的其他病毒属于星状病毒科、杯状病毒科和冠状病毒科。其中一些病毒可能具有潜在的跨种传播能力，而其他病毒则表明鸭属病毒的遗传多样性很广。该研究还表明，沿东亚-澳大拉西亚候鸟迁徙路线传播病毒的可能性，这可能是由迁徙的滨鸟促成的。检测和鉴定了几种以前未描述的、引起无症状但也可能引起有症状感染的禽病毒，这表明需要对野生动物宿主中的致病性和潜在人畜共患病病毒进行更多的病毒监测研究。
