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14至15岁丹麦青少年的患病率及牙周检查结果:一项描述性横断面研究。

Prevalence of and Periodontal Findings among 14 to 15-Year Old Danish Adolescents: A Descriptive Cross-Sectional Study.

作者信息

Jensen Anne Birkeholm, Isidor Flemming, Lund Marianne, Væth Michael, Johansson Anders, Lauritsen Niels Nørskov, Haubek Dorte

机构信息

Section for Pediatric Dentistry, Department of Dentistry and Oral Health, Health, Aarhus University, 8000 Aarhus, Denmark.

The Municipality of Aarhus, 8000 Aarhus, Denmark.

出版信息

Pathogens. 2020 Dec 16;9(12):1054. doi: 10.3390/pathogens9121054.

Abstract

() is a keystone pathogen associated with periodontitis in adolescents. The knowledge on the prevalence of and periodontitis among adolescents in Northern Europe is sparse. A total of 525 14- to 15-year-old adolescents from the municipality of Aarhus, Denmark, underwent a full-mouth clinical examination. Plaque score (PS), bleeding on probing (BOP), probing pocket depth (PPD), and clinical attachment loss (CAL) were recorded. Subgingival plaque samples (SPS) and stimulated saliva samples (SSS) were collected and analyzed for the presence of JP2 and non-JP2 genotypes of using real-time PCR. A total of 70 (13.3%) individuals were positive for , with 17 found in SPS, 19 in SSS, and 35 in both. The highly leukotoxic JP2 genotype of was not detected. The individuals positive for in both SPS and SSS had poorer periodontal outcomes (PPD and CAL) than individuals without and individuals carrying in either SPS or SSS only. In conclusion, 13% of 14- to 15-year-old Danish adolescents were positive for , and the presence of in both SPS and SSS was associated with poorer periodontal outcomes.

摘要

()是与青少年牙周炎相关的关键病原体。关于北欧青少年中()和牙周炎患病率的知识较为匮乏。来自丹麦奥胡斯市的525名14至15岁青少年接受了全口临床检查。记录了菌斑评分(PS)、探诊出血(BOP)、探诊袋深度(PPD)和临床附着丧失(CAL)。收集龈下菌斑样本(SPS)和刺激唾液样本(SSS),并使用实时PCR分析其中()的JP2和非JP2基因型的存在情况。共有70名(13.3%)个体检测出()呈阳性,其中17例在SPS中检测到,19例在SSS中检测到,35例在两者中均检测到。未检测到具有高度白细胞毒性的()的JP2基因型。在SPS和SSS中均检测出()呈阳性的个体,其牙周状况(PPD和CAL)比未检测到()的个体以及仅在SPS或SSS中检测到()的个体更差。总之,13%的14至15岁丹麦青少年检测出()呈阳性,且SPS和SSS中均存在()与较差的牙周状况相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca7d/7765784/ea0aa44f5944/pathogens-09-01054-g001.jpg

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