França Katlein
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Dermatol Ther (Heidelb). 2021 Feb;11(1):71-77. doi: 10.1007/s13555-020-00476-7. Epub 2020 Dec 19.
Recent studies have produced an increasing body of evidence that the intestinal microbiome plays an essential role in modulating systemic inflammation and skin diseases. The gut microbiome influences and modulates the host immune system, enabling immune tolerance of environmental and dietary antigens and protecting against pathogens. Emerging scientific evidence has demonstrated that oral probiotics can help treat certain skin diseases, such as acne, atopic dermatitis, photoaging, psoriasis, and wound healing. The aim of this paper is to review the current scientific evidence on topical probiotics and their effects on dermatological diseases and skincare and to clarify if the application of exogenous probiotics could also have the same benefit as oral probiotics in promoting positive bacterial balance to treat dermatologic conditions.
最近的研究产生了越来越多的证据表明，肠道微生物群在调节全身炎症和皮肤疾病中起着至关重要的作用。肠道微生物群影响并调节宿主免疫系统，实现对环境和饮食抗原的免疫耐受并抵御病原体。新出现的科学证据表明，口服益生菌有助于治疗某些皮肤疾病，如痤疮、特应性皮炎、光老化、银屑病和伤口愈合。本文的目的是综述目前关于局部应用益生菌及其对皮肤病和皮肤护理影响的科学证据，并阐明外用益生菌在促进有益细菌平衡以治疗皮肤病方面是否也能与口服益生菌具有相同的益处。
