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Asprosin in pregnancy and childhood.

作者信息

Janoschek Ruth, Hoffmann Thorben, Morcos Yousef Ashraf Tawfik, Sengle Gerhard, Dötsch Jörg, Hucklenbruch-Rother Eva

机构信息

Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.

Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

出版信息

Mol Cell Pediatr. 2020 Dec 23;7(1):18. doi: 10.1186/s40348-020-00110-8.

DOI:10.1186/s40348-020-00110-8
PMID:33354737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7755955/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a879/7755955/c4c5488c1d1d/40348_2020_110_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a879/7755955/c4c5488c1d1d/40348_2020_110_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a879/7755955/c4c5488c1d1d/40348_2020_110_Fig1_HTML.jpg

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Asprosin in pregnancy and childhood.妊娠和儿童期的阿朴脂蛋白
Mol Cell Pediatr. 2020 Dec 23;7(1):18. doi: 10.1186/s40348-020-00110-8.
2
Asprosin in umbilical cord of newborns and maternal blood of gestational diabetes, preeclampsia, severe preeclampsia, intrauterine growth retardation and macrosemic fetus.新生儿脐带和妊娠糖尿病、子痫前期、重度子痫前期、宫内生长受限及巨大胎儿孕妇血中的去唾液酸糖蛋白受体。
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3
[Effect of high-fat diet and exercise on asprosin and CTRP6 expression in subcutaneous and retroperitoneal adipose tissues in rats during mid-gestation].高脂饮食与运动对妊娠中期大鼠皮下及腹膜后脂肪组织中阿朴脂蛋白和CTRP6表达的影响
Nan Fang Yi Ke Da Xue Xue Bao. 2020 Oct 30;40(10):1406-1414. doi: 10.12122/j.issn.1673-4254.2020.10.05.
4
Serum Asprosin Concentrations Are Increased and Associated with Insulin Resistance in Children with Obesity.血清阿普索林浓度升高与肥胖儿童的胰岛素抵抗有关。
Ann Nutr Metab. 2019;75(4):205-212. doi: 10.1159/000503808. Epub 2019 Nov 27.
5
Decreased Circulating Levels of Asprosin in Obese Children.肥胖儿童循环中阿普斯灵水平降低。
Horm Res Paediatr. 2019;91(4):271-277. doi: 10.1159/000500523. Epub 2019 Jun 18.
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Aerobic Exercise Training Decreases Hepatic Asprosin in Diabetic Rats.有氧运动训练可降低糖尿病大鼠肝脏中的阿朴脂蛋白
J Clin Med. 2019 May 12;8(5):666. doi: 10.3390/jcm8050666.
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Acute Anaerobic Exercise Affects the Secretion of Asprosin, Irisin, and Other Cytokines - A Comparison Between Sexes.急性无氧运动对阿朴脂蛋白、鸢尾素及其他细胞因子分泌的影响——一项性别间的比较
Front Physiol. 2018 Dec 10;9:1782. doi: 10.3389/fphys.2018.01782. eCollection 2018.
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Asprosin: a novel peptide hormone related to insulin resistance in women with polycystic ovary syndrome.阿朴脂蛋白：一种与多囊卵巢综合征女性胰岛素抵抗相关的新型肽类激素。
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Circulating asprosin concentrations are increased in type 2 diabetes mellitus and independently associated with fasting glucose and triglyceride.在 2 型糖尿病患者中，循环中的 aspresin 浓度升高，并且与空腹血糖和甘油三酯独立相关。
Clin Chim Acta. 2019 Feb;489:183-188. doi: 10.1016/j.cca.2017.10.034. Epub 2017 Nov 3.
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Asprosin attenuates insulin signaling pathway through PKCδ-activated ER stress and inflammation in skeletal muscle.脑啡肽原通过蛋白激酶 Cδ激活的内质网应激和肌肉炎症来减弱胰岛素信号通路。
J Cell Physiol. 2019 Nov;234(11):20888-20899. doi: 10.1002/jcp.28694. Epub 2019 Apr 17.

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The secretory function of adipose tissues in metabolic regulation.脂肪组织在代谢调节中的分泌功能。
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Development of a mix-and-read assay for human asprosin using antibody-oligonucleotide probes and thermofluorimetric analysis.使用抗体-寡核苷酸探针和热荧光分析技术开发人嗜蛋白原混合读取检测法。
Anal Methods. 2024 Sep 12;16(35):6057-6063. doi: 10.1039/d3ay01175e.
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Association of serum asprosin with metabolic dysfunction-associated fatty liver disease in older adult type 2 diabetic patients: a cross-sectional study.

本文引用的文献

1
Investigation of plasma asprosin and saliva levels in newly diagnosed type 2 diabetes mellitus patients treated with metformin.探讨二甲双胍治疗初诊 2 型糖尿病患者的血浆 asparosin 和唾液水平。
Endokrynol Pol. 2021;72(1):37-43. doi: 10.5603/EP.a2020.0059. Epub 2020 Sep 18.
2
Fibrillin-1 and fibrillin-1-derived asprosin in adipose tissue function and metabolic disorders.脂肪组织功能与代谢紊乱中的原纤蛋白-1及源自原纤蛋白-1的阿朴脂蛋白
J Cell Commun Signal. 2020 Jun;14(2):159-173. doi: 10.1007/s12079-020-00566-3. Epub 2020 Apr 12.
3
Continuous elevation of plasma asprosin in pregnant women complicated with gestational diabetes mellitus: A nested case-control study.
血清阿普瑞素与老年 2 型糖尿病患者代谢相关脂肪性肝病的相关性：一项横断面研究。
BMC Endocr Disord. 2024 Mar 4;24(1):27. doi: 10.1186/s12902-024-01560-1.
4
Protein tyrosine phosphatase receptor δ serves as the orexigenic asprosin receptor.蛋白酪氨酸磷酸酶受体 δ 作为食欲素的受体发挥作用。
Cell Metab. 2022 Apr 5;34(4):549-563.e8. doi: 10.1016/j.cmet.2022.02.012. Epub 2022 Mar 16.
5
Correlation of metabolic characteristics with maternal, fetal and placental asprosin in human pregnancy.人类妊娠中代谢特征与母体、胎儿及胎盘抑脂素的相关性
Endocr Connect. 2022 Mar 14;11(3):e220069. doi: 10.1530/EC-22-0069.
6
Sensitive asprosin detection in clinical samples reveals serum/saliva correlation and indicates cartilage as source for serum asprosin.在临床样本中进行敏感的 asprosin 检测可揭示血清/唾液的相关性，并表明软骨是血清 asprosin 的来源。
Sci Rep. 2022 Jan 25;12(1):1340. doi: 10.1038/s41598-022-05060-x.
7
Asprosin-A Fasting-Induced, Glucogenic, and Orexigenic Adipokine as a New Promising Player. Will It Be a New Factor in the Treatment of Obesity, Diabetes, or Infertility? A Review of the Literature.阿普索辛——一种禁食诱导的、产糖的、食欲刺激的脂肪因子，作为一种有前途的新分子。它会成为肥胖症、糖尿病或不孕症治疗的新因素吗？文献综述。
Nutrients. 2021 Feb 14;13(2):620. doi: 10.3390/nu13020620.
妊娠期糖尿病孕妇血浆嗜天门冬氨酸持续升高：巢式病例对照研究。
Placenta. 2020 Apr;93:17-22. doi: 10.1016/j.placenta.2020.02.004. Epub 2020 Feb 7.
4
Increased serum circulating asprosin levels in children with obesity.肥胖儿童血清循环中天门冬氨酸的水平升高。
Pediatr Int. 2020 Apr;62(4):467-476. doi: 10.1111/ped.14176.
5
Serum Asprosin Concentrations Are Increased and Associated with Insulin Resistance in Children with Obesity.血清阿普索林浓度升高与肥胖儿童的胰岛素抵抗有关。
Ann Nutr Metab. 2019;75(4):205-212. doi: 10.1159/000503808. Epub 2019 Nov 27.
6
Asprosin in umbilical cord of newborns and maternal blood of gestational diabetes, preeclampsia, severe preeclampsia, intrauterine growth retardation and macrosemic fetus.新生儿脐带和妊娠糖尿病、子痫前期、重度子痫前期、宫内生长受限及巨大胎儿孕妇血中的去唾液酸糖蛋白受体。
Peptides. 2019 Oct;120:170132. doi: 10.1016/j.peptides.2019.170132. Epub 2019 Aug 7.
7
OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin.OLFR734 作为天冬酰胺酶的受体介导葡萄糖代谢。
Cell Metab. 2019 Aug 6;30(2):319-328.e8. doi: 10.1016/j.cmet.2019.05.022. Epub 2019 Jun 20.
8
Decreased Circulating Levels of Asprosin in Obese Children.肥胖儿童循环中阿普斯灵水平降低。
Horm Res Paediatr. 2019;91(4):271-277. doi: 10.1159/000500523. Epub 2019 Jun 18.
9
Saliva and Blood Asprosin Hormone Concentration Associated with Obesity.唾液和血液中阿普洛辛激素浓度与肥胖的关系。
Int J Endocrinol. 2019 Mar 27;2019:2521096. doi: 10.1155/2019/2521096. eCollection 2019.
10
Asprosin attenuates insulin signaling pathway through PKCδ-activated ER stress and inflammation in skeletal muscle.脑啡肽原通过蛋白激酶 Cδ激活的内质网应激和肌肉炎症来减弱胰岛素信号通路。
J Cell Physiol. 2019 Nov;234(11):20888-20899. doi: 10.1002/jcp.28694. Epub 2019 Apr 17.