Wiecek Magdalena, Szymura Jadwiga, Maciejczyk Marcin, Kantorowicz Malgorzata, Szygula Zbigniew
Department of Physiology and Biochemistry, Faculty of Physical Education and Sport, University of Physical Education in Krakow, Kraków, Poland.
Department of Clinical Rehabilitation, Faculty of Motor Rehabilitation, University of Physical Education in Krakow, Kraków, Poland.
Front Physiol. 2018 Dec 10;9:1782. doi: 10.3389/fphys.2018.01782. eCollection 2018.
The new adipokine, which is asprosin, affects glucose release from the liver to the blood, and thus, influences exercise metabolism. This is the first study assessing whether single anaerobic exercise affects asprosin secretion in women and men. 10 men and 10 women (aged 21.64 ± 1.22 and 22.64 ± 1.49, respectively) performed a single 20-s bicycle sprint. Blood samples were collected before exercise and in the 3', 15', 30', and 60' of recovery, and 24 h after competition. Only in women did asprosin ( = 0.001) (15', 30', 60', and 24 h after exercise) and irisin ( < 0.001) (15', 30', and 60') concentrations increase. Leptin, however, decreased ( = 0.001) at 3', 15', and 30' in women. There was an increase in interleukin-6 ( < 0.001) at 3', 15', 30', and 60' of recovery in men, at 15', 30', 60', and 24 h of recovery in women, along with a simultaneous decrease in interleukin-1β ( < 0.001) at 15', 30', and 60' of recovery in men, and at 15' and 30' of recovery in women ( = -0.35, < 0.001). There was a positive correlation between asprosin and adiponectin and a negative one between asprosin and leptin. The increase in irisin concentration at 30' of recovery was positively correlated with the increase in asprosin concentration and percentage fat content, while being negatively correlated with total and lean body mass (LBM). The single anaerobic effort induced an increase in asprosin and irisin secretion while reducing leptin secretion in women. Adipocytokine concentration changes are inter-related. Regardless of sex, anaerobic efforts induce anti-inflammatory effects.
这种新的脂肪因子——促脂素，会影响肝脏向血液中释放葡萄糖，进而影响运动代谢。这是第一项评估单次无氧运动是否会影响男性和女性促脂素分泌的研究。10名男性和10名女性（年龄分别为21.64±1.22岁和22.64±1.49岁）进行了一次20秒的自行车冲刺。在运动前、恢复的第3分钟、15分钟、30分钟和60分钟以及比赛后24小时采集血样。仅在女性中，促脂素（运动后15分钟、30分钟、60分钟和24小时）和鸢尾素（运动后15分钟、30分钟和60分钟）的浓度升高。然而，女性在运动后第3分钟、15分钟和30分钟时瘦素水平下降（P = 0.001）。男性恢复过程中第3分钟、15分钟、30分钟和60分钟时白细胞介素-6升高（P < 0.001），女性恢复过程中第15分钟、30分钟、60分钟和24小时时白细胞介素-6升高，同时男性恢复过程中第15分钟、30分钟和60分钟时白细胞介素-1β下降（P < 0.001），女性恢复过程中第15分钟和30分钟时白细胞介素-1β下降（r = -0.35，P < 0.001）。促脂素与脂联素呈正相关，与瘦素呈负相关。恢复30分钟时鸢尾素浓度的升高与促脂素浓度的升高和脂肪含量百分比呈正相关，而与总体重和去脂体重呈负相关。单次无氧运动使女性促脂素和鸢尾素分泌增加，同时瘦素分泌减少。脂肪细胞因子浓度变化相互关联。无论性别如何，无氧运动都会产生抗炎作用。
