Santiago-Torres Margarita, Shi Zaixing, Tinker Lesley F, Lampe Johanna W, Allison Matthew A, Barrington Wendy, Crane Tracy E, Garcia David O, Hayden Kathleen M, Isasi Carmen R, Valdiviezo-Schlomp Carolina I, Martin Lisa W, Neuhouser Marian L
Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Department of Family Medicine and Public Health, University of California San Diego, CA, USA.
Nutr Healthy Aging. 2020 Nov 3;5(4):261-272. doi: 10.3233/NHA-190076.
The prevalence of metabolic syndrome is higher among minority populations, including individuals of Mexican ethnic descent. Whether alignment to healthy dietary patterns is associated with lower risk of metabolic syndrome in this population is largely unknown.
To prospectively evaluate the associations between diet quality scores and risk of metabolic syndrome and its components among postmenopausal women of Mexican ethnic descent.
A total of 334 women of Mexican ethnic descent who participated in the Women's Health Initiative (WHI) observational study without metabolic syndrome or diabetes at baseline (1993-1998) were included. Baseline diets were scored with the Alternate Mediterranean Diet (aMED), the Dietary Approaches to Stop Hypertension (DASH), the Healthy Eating Index (HEI-2010), the Mediterranean Diet Score (MDS), and the traditional Mexican Diet (MexD) score. Multivariable linear and logistic regression models were used to test the associations between baseline diet quality and risk of metabolic syndrome and its individual components at follow-up (2012-2013).
Approximately 16% of women met the criteria for metabolic syndrome at follow-up. None of the diet quality indices were associated with risk of metabolic syndrome. However, higher vs lower DASH scores were associated with lower waist circumference (85.2 vs 88.0 cm) and glucose concentrations (90.0 vs 95.1 mg/dL), and higher HDL cholesterol (62.6 vs 59.0 mg/dL), while higher vs lower HEI-2010 scores were associated with lower waist circumference (83.9 vs 88.1 cm), triglycerides (103 vs 117 mg/dL) and glucose concentrations (89.5 vs 94.4 mg/dL), and higher HDL cholesterol levels (63.9 vs 58.5 mg/dL).
Diet quality was not associated with risk of metabolic syndrome in this population. However, the results suggest that alignment to DASH and HEI-2010 recommendations may be beneficial for reducing some individual components of metabolic syndrome among postmenopausal women of Mexican descent.
代谢综合征在少数族裔人群中更为普遍，包括墨西哥裔个体。在这一人群中，遵循健康饮食模式是否与较低的代谢综合征风险相关，目前很大程度上尚不清楚。
前瞻性评估墨西哥裔绝经后女性的饮食质量得分与代谢综合征及其组分风险之间的关联。
纳入了总共334名墨西哥裔女性，她们参加了女性健康倡议（WHI）观察性研究，基线时（1993 - 1998年）无代谢综合征或糖尿病。基线饮食采用替代地中海饮食（aMED）、终止高血压饮食方法（DASH）、健康饮食指数（HEI - 2010）、地中海饮食评分（MDS）以及传统墨西哥饮食（MexD）评分。多变量线性和逻辑回归模型用于检验基线饮食质量与随访时（2012 - 2013年）代谢综合征及其个体组分风险之间的关联。
随访时约16%的女性符合代谢综合征标准。没有任何饮食质量指标与代谢综合征风险相关。然而，较高的DASH得分与较低的腰围（85.2对88.0厘米）、血糖浓度（90.0对95.1毫克/分升）以及较高的高密度脂蛋白胆固醇（62.6对59.0毫克/分升）相关，而较高的HEI - 2010得分与较低的腰围（83.9对88.1厘米）、甘油三酯（103对11 | 7毫克/分升）、血糖浓度（89.5对94.4毫克/分升）以及较高的高密度脂蛋白胆固醇水平（63.9对58.5毫克/分升）相关。
该人群的饮食质量与代谢综合征风险无关。然而，结果表明遵循DASH和HEI - 2010建议可能有利于降低墨西哥裔绝经后女性代谢综合征的一些个体组分。
