Xu Longqian, Hu Chenxuan, Huang Qi, Jin Kai, Zhao Ping, Wang Dongping, Hou Wei, Dong Lihua, Hu Siyi, Ma Hanbin
CAS Key Laboratory of Bio-medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, No.88 Keling Road, Suzhou, Jiangsu province, 215163, PR China.
CAS Key Laboratory of Bio-medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, No.88 Keling Road, Suzhou, Jiangsu province, 215163, PR China; International Joint Research Center for Nanophotonics and Biophotonics, School of Science, Changchun University of Science and Technology, Changchun, Jilin province, 130022, PR China.
Biosens Bioelectron. 2021 Mar 1;175:112854. doi: 10.1016/j.bios.2020.112854. Epub 2020 Nov 26.
In this paper, we reviewed the history of microelectrode arrays (MEAs), compared different microfabrication techniques applied to modern MEAs in terms of their material characters, device properties and application scenarios. Then we discussed the biocompatibility of different MEAs as well as corresponding strategy of improvement. At last, we analyzed the growing trend of MEAs' technical route, expected application of MEAs in the field of Electrical impedance tomography (EIT).
在本文中,我们回顾了微电极阵列(MEA)的历史,比较了应用于现代MEA的不同微制造技术在材料特性、器件性能和应用场景方面的差异。然后我们讨论了不同MEA的生物相容性以及相应的改进策略。最后,我们分析了MEA技术路线的发展趋势,以及MEA在电阻抗断层成像(EIT)领域的预期应用。