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比色法检测真菌毒素的研究进展:迈向快速工业监测。

Advances in Colorimetric Strategies for Mycotoxins Detection: Toward Rapid Industrial Monitoring.

机构信息

Department of Food Science & Technology, School of Agriculture, Shiraz University, Shiraz 71441-65186, Iran.

BAE-LBBM Laboratory, University of Perpignan via Domitia, 52 Avenue Paul Alduy, CEDEX 9, 66860 Perpignan, France.

出版信息

Toxins (Basel). 2020 Dec 24;13(1):13. doi: 10.3390/toxins13010013.

Abstract

Mycotoxins contamination is a global public health concern. Therefore, highly sensitive and selective techniques are needed for their on-site monitoring. Several approaches are conceivable for mycotoxins analysis, among which colorimetric methods are the most attractive for commercialization purposes thanks to their visual read-out, easy operation, cost-effectiveness, and rapid response. This review covers the latest achievements in the last five years for the development of colorimetric methods specific to mycotoxins analysis, with a particular emphasis on their potential for large-scale applications in food industries. Gathering all types of (bio)receptors, main colorimetric methods are critically discussed, including enzyme-linked assays, lateral flow-assays, microfluidic devices, and homogenous in-solution strategies. This special focus on colorimetry as a versatile transduction method for mycotoxins analysis is comprehensively reviewed for the first time.

摘要

真菌毒素污染是一个全球性的公共卫生关注点。因此,需要高度敏感和选择性的技术来进行现场监测。有几种方法可以用于真菌毒素分析,其中比色法因其可视化读取、易于操作、经济高效和快速响应而最具商业化吸引力。本文综述了过去五年中在开发针对真菌毒素分析的比色法方面的最新进展,特别强调了它们在食品工业中的大规模应用潜力。本文综述了各种(生物)受体,重点讨论了主要的比色法,包括酶联测定法、横向流动测定法、微流控装置和均相溶液内策略。这是首次全面综述比色法作为一种用于真菌毒素分析的多功能转换方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0695/7823678/7ad5dcbff4bc/toxins-13-00013-g001.jpg

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