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茶氨酸及其对健康的有益影响。 （原英文标题表述不太准确规范，推测可能是想表达Theanine From... ）

Theacrine From and Its Health Beneficial Effects.

作者信息

Sheng Yue-Yue, Xiang Jing, Wang Ze-Shi, Jin Jing, Wang Ying-Qi, Li Qing-Sheng, Li Da, Fang Zhou-Tao, Lu Jian-Liang, Ye Jian-Hui, Liang Yue-Rong, Zheng Xin-Qiang

机构信息

Tea Research Institute, Zhejiang University, Hangzhou, China.

Zhejiang Agricultural Technology Extension Center, Hangzhou, China.

出版信息

Front Nutr. 2020 Dec 17;7:596823. doi: 10.3389/fnut.2020.596823. eCollection 2020.

DOI:10.3389/fnut.2020.596823
PMID:33392238
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7773691/
Abstract

Theacrine, i.e., 1,3,7,9-tetramethyluric acid, is one of the major purine alkaloids found in leaf of a wild tea plant species Hung T. Chang. Theacrine has been attracted great attentions academically owing to its diverse health benefits. Present review examines the advances in the research on the health beneficial effects of theacrine, including antioxidant effect, anti-inflammatory effect, locomotor activation and reducing fatigue effects, improving cognitive effect, hypnotic effect, ameliorating lipid metabolism and inhibiting breast cancer cell metastasis effect. The inconsistent results in this research field and further expectations were also discussed.

摘要

茶氨酸，即1,3,7,9 - 四甲基尿酸，是在野生茶树物种（张宏达）叶片中发现的主要嘌呤生物碱之一。茶氨酸因其多样的健康益处而在学术上备受关注。本综述考察了茶氨酸对健康有益作用的研究进展，包括抗氧化作用、抗炎作用、运动激活和减轻疲劳作用、改善认知作用、催眠作用、改善脂质代谢以及抑制乳腺癌细胞转移作用。还讨论了该研究领域中不一致的结果以及进一步的期望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2495/7773691/99e4906b3850/fnut-07-596823-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2495/7773691/5a762e152d51/fnut-07-596823-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2495/7773691/a3071893f72b/fnut-07-596823-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2495/7773691/99e4906b3850/fnut-07-596823-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2495/7773691/5a762e152d51/fnut-07-596823-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2495/7773691/a3071893f72b/fnut-07-596823-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2495/7773691/99e4906b3850/fnut-07-596823-g0003.jpg

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Theacrine From and Its Health Beneficial Effects.茶氨酸及其对健康的有益影响。 （原英文标题表述不太准确规范，推测可能是想表达Theanine From... ）
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J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Oct 15;1155:122278. doi: 10.1016/j.jchromb.2020.122278. Epub 2020 Aug 2.
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Theacrine and strictinin, two major ingredients for the anti-influenza activity of Yunnan Kucha tea.云南苦茶抗流感活性的两大主要成分：可可因和斯克里廷。
J Ethnopharmacol. 2020 Nov 15;262:113190. doi: 10.1016/j.jep.2020.113190. Epub 2020 Jul 27.
3
对狭叶咖啡类似阿拉比卡咖啡风味及优质咖啡化学特性的代谢组学见解。
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Dose response effects of theacrine on cognitive performance and subsequent sleep.瓜拉纳对认知表现和随后睡眠的剂量反应影响。
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The Effect of Short-Term NAD3® Supplementation on Circulating Adult Stem Cells in Healthy Individuals Aged 40-70 Years.短期补充NAD3®对40 - 70岁健康个体循环成体干细胞的影响
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