Taiwo Adewale Matthew
Department of Environmental Management and Toxicology, Federal University of Agriculture, PMB, 2240, Abeokuta, Ogun State, Nigeria.
Chemosphere. 2019 Apr;220:1126-1140. doi: 10.1016/j.chemosphere.2019.01.001. Epub 2019 Jan 2.
Organochlorine pesticides (OCPs) are generally categorized as chlorinated cyclodienes, chlorodiphenylethanes, chlorinated benzenes and cyclohexanes. The presence of OCP residues in foodstuffs, water, soil, sediments, blood serum and air has generated a surge of global interest. This is due to their severe environmental and health ill-effects. OCPs are characteristically described as persistent and bio-accumulating substances prone to long-range transportation. The aim of this present study is to assess the environmental and health risks associated with OCP residues. Published works on OCPs in surface water, sediments and fish samples were reviewed. Possible non-carcinogenic (Hazard Quotient, HQ and Hazard Index, HI) and carcinogenic (Cancer Risk, CR) health effects of OCPs were assessed in fish samples. High concentrations of OCP residues were determined in environmental samples from African countries. The non-carcinogenic health assessment of OCPs in most fish samples from Nigeria revealed HI values greater than 1.0 establishing their adverse effects. The CR data of OCPs in fish samples also showed values higher than the permissible standard of 1.0 × 10 indicating possible development of cancer through fish consumption.
有机氯农药（OCPs）通常分为氯代环二烯类、氯代二苯乙烷类、氯代苯类和环己烷类。食品、水、土壤、沉积物、血清和空气中存在的有机氯农药残留引发了全球的广泛关注。这是由于它们对环境和健康有严重的不良影响。有机氯农药的特点是被描述为具有持久性和生物累积性的物质，易于远距离传输。本研究的目的是评估与有机氯农药残留相关的环境和健康风险。对已发表的关于地表水、沉积物和鱼类样本中有机氯农药的研究进行了综述。评估了鱼类样本中有机氯农药可能产生的非致癌（危害商数，HQ和危害指数，HI）和致癌（癌症风险，CR）健康影响。在非洲国家的环境样本中检测到高浓度的有机氯农药残留。对尼日利亚大多数鱼类样本中有机氯农药的非致癌健康评估显示，危害指数值大于1.0，表明它们具有不良影响。鱼类样本中有机氯农药的癌症风险数据也显示高于1.0×10的可接受标准，表明通过食用鱼类可能会引发癌症。
