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脉络膜血液灌注作为近视发生发展的潜在“快速预测指标”。

Choroidal blood perfusion as a potential "rapid predictive index" for myopia development and progression.

作者信息

Zhou Xiangtian, Ye Cong, Wang Xiaoyan, Zhou Weihe, Reinach Peter, Qu Jia

机构信息

Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.

National Clinical Research Center for Ocular Diseases, Wenzhou, Zhejiang, China.

出版信息

Eye Vis (Lond). 2021 Jan 4;8(1):1. doi: 10.1186/s40662-020-00224-0.

DOI:10.1186/s40662-020-00224-0
PMID:33397473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7780679/
Abstract

Myopia is the leading cause of visual impairment worldwide. The lack of a "rapid predictive index" for myopia development and progression hinders the clinic management and prevention of myopia. This article reviews the studies describing changes that occur in the choroid during myopia development and proposes that it is possible to detect myopia development at an earlier stage than is currently possible in a clinical setting using choroidal blood perfusion as a "rapid predictive index" of myopia.

摘要

近视是全球视力损害的主要原因。缺乏用于近视发展和进展的“快速预测指标”阻碍了近视的临床管理和预防。本文回顾了描述近视发展过程中脉络膜发生变化的研究,并提出利用脉络膜血流灌注作为近视的“快速预测指标”,有可能在临床环境中比目前更早地检测到近视的发展。

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本文引用的文献

1
Assessment of Choroidal Vascularity and Choriocapillaris Blood Perfusion in Anisomyopic Adults by SS-OCT/OCTA.利用 SS-OCT/OCTA 评估屈光参差成年人的脉络膜血管和脉络膜毛细血管血流。
Invest Ophthalmol Vis Sci. 2021 Jan 4;62(1):8. doi: 10.1167/iovs.62.1.8.
2
Increased Choroidal Blood Perfusion Can Inhibit Form Deprivation Myopia in Guinea Pigs.脉络膜血流增加可抑制豚鼠形觉剥夺性近视。
Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):25. doi: 10.1167/iovs.61.13.25.
3
Changes in Choroidal Thickness Varied by Age and Refraction in Children and Adolescents: A 1-Year Longitudinal Study.儿童和青少年脉络膜厚度随年龄和屈光度的变化:一项为期 1 年的纵向研究。
Am J Ophthalmol. 2020 May;213:46-56. doi: 10.1016/j.ajo.2020.01.003. Epub 2020 Jan 13.
4
Demyelination and shrinkage of axons in the retinal nerve fiber layer in chickens developing deprivation myopia.鸡发育性近视中视网膜神经纤维层的髓鞘脱失和轴突缩小。
Exp Eye Res. 2019 Nov;188:107783. doi: 10.1016/j.exer.2019.107783. Epub 2019 Aug 29.
5
Changes in Choroidal Thickness and Choroidal Blood Perfusion in Guinea Pig Myopia.豚鼠近视模型脉络膜厚度和脉络膜血流的变化。
Invest Ophthalmol Vis Sci. 2019 Jul 1;60(8):3074-3083. doi: 10.1167/iovs.18-26397.
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Biomed Opt Express. 2019 Mar 13;10(4):1822-1840. doi: 10.1364/BOE.10.001822. eCollection 2019 Apr 1.
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Graefes Arch Clin Exp Ophthalmol. 2018 Aug;256(8):1419-1427. doi: 10.1007/s00417-018-4012-y. Epub 2018 Jun 6.