Lepekhova Anfisa, Dunaeva Ekaterina, Teplyuk Natalia, Vertieva Ekaterina
Sechenov University, Department of Dermatology and Venereology, Moscow, Russian Federation.
Dermatol Reports. 2020 Sep 24;12(2):8372. doi: 10.4081/dr.2020.8372. eCollection 2020 Sep 23.
Buschke-Löwenstein tumor is known to manifest not only in sexually active people and adolescents exposed to violence or drugs, but also in people who do not have any predisposing factors or bad habits. Several studies have shown that in the majority of children with anogenital warts, HPV can be transmitted asexually by hetero- inoculation or through infected objects. To our knowledge, there are currently few reports on BLT in HPV-negative patients in the literature. In our case, the patient presented early, with multiple slow growing warts, no history of alcohol intake, drug use or smoking and no HPV infection, which makes this case unique and important.
Buschke-Löwenstein瘤不仅见于有性活动的人群以及遭受暴力或吸毒的青少年，也见于没有任何易感因素或不良习惯的人群。多项研究表明，在大多数患有肛门生殖器疣的儿童中，人乳头瘤病毒（HPV）可通过异体接种或接触受感染物体而无性传播。据我们所知，目前文献中关于HPV阴性患者的Buschke-Löwenstein瘤的报道很少。在我们的病例中，患者就诊较早，有多个生长缓慢的疣体，无饮酒、吸毒或吸烟史，且未感染HPV，这使得该病例独特且重要。
