Buckley Colman, Fabert Marc, Kinet Damien, Kucikas Vytautas, Pagnoux Dominique
University of Limoges, CNRS, Xlim, UMR 7252, F-87000 Limoges, France.
University of Mons, Faculté Polytechnique, Bd Dolez 31, B-7000 Mons, Belgium.
Biomed Opt Express. 2020 Nov 10;11(12):7032-7052. doi: 10.1364/BOE.403157. eCollection 2020 Dec 1.
We report on a novel endomicroscope, to the best of our knowledge, designed for achieving full 4×4 Mueller polarimetric images of biological tissues through a fiber endoscope for medical diagnosis. The polarimetric technique is based on a previously published two-wavelength differential method (TWDM). A key component of the endomicroscope is a resonant fiber-based microprobe including a highly-selective fiber Bragg grating (FBG), free of detrimental polarimetric effects, photo written in the core of the fiber, near the output face. By means of the TWDM, and using the specially designed microprobe (diameter 2.9 mm, length 30 mm), full Mueller images of 250×250 pixels were produced at the rate of 1 image/2 s through a 2 m single mode fiber, paving the way to applications in polarimetric endomicroscopy.
据我们所知，我们报道了一种新型的内窥镜，其设计目的是通过用于医学诊断的纤维内窥镜获取生物组织的完整4×4穆勒偏振图像。偏振技术基于先前发表的双波长差分法（TWDM）。该内窥镜的一个关键部件是基于共振光纤的微探针，其包括一个高选择性光纤布拉格光栅（FBG），该光栅在光纤芯中靠近输出面处光写入，无有害偏振效应。借助TWDM，并使用专门设计的微探针（直径2.9毫米，长度30毫米），通过2米单模光纤以每秒1幅图像的速率生成了250×250像素的完整穆勒图像，为偏振内窥镜的应用铺平了道路。
