Department of Public Health and Paediatric Sciences, University of Turin, Torino, Italy.
Department of Public Health and Paediatric Sciences, University of Turin, Torino, Italy.
Vaccine. 2021 Feb 5;39(6):901-914. doi: 10.1016/j.vaccine.2020.12.061. Epub 2021 Jan 12.
Influenza is a disease responsible for thousands of deaths every year. Although healthcare workers (HCWs) represent a way of contagion for patients, vaccination coverage among them is low. Mandatory vaccination has been proposed, but controversies remain. This systematic review and meta-analysis aimed to assess the acceptance of mandatory vaccination by HCWs, and to investigate associated characteristics. MEDLINE, Scopus, Embase, PsycInfo, CINAHL and Web of Science were used to search for studies assessing the topic. PRISMA statements were followed. Of the 13,457 univocal records found, 52 studies were included in the systematic review and 40 in the meta-analysis. The pooled proportion of HCWs accepting the policy was of 61% (95% CI: 53%- 68%) but with great heterogeneity between continents (from 54% in Europe to 69% in Asia) and in different professionals (from 40% in nurses to 80% in students). Vaccinated HCWs agreed more frequently with mandatory vaccination than non-vaccinated ones. More studies that consider mandatory vaccination acceptance as the main outcome are needed, but the results of this study confirm that in some settings the majority of HCWs favour mandatory vaccination. This, combined with effects that a flu epidemic could have if overlapped to pandemics with similar symptoms, requires renewed considerations on mandatory vaccination.
流感每年导致数千人死亡。尽管医护人员（HCWs）是患者感染的一种途径，但他们的疫苗接种率很低。已经提出了强制性接种疫苗的建议，但仍存在争议。本系统评价和荟萃分析旨在评估 HCWs 对强制性疫苗接种的接受程度，并研究相关特征。使用 MEDLINE、Scopus、Embase、PsycInfo、CINAHL 和 Web of Science 搜索评估该主题的研究。遵循 PRISMA 声明。在 13457 条非重复记录中，有 52 项研究被纳入系统评价，40 项研究被纳入荟萃分析。HCWs 接受该政策的比例为 61%（95%CI：53%-68%），但在各大洲之间存在很大异质性（从欧洲的 54%到亚洲的 69%），不同专业之间也存在异质性（从护士的 40%到学生的 80%）。接种疫苗的 HCWs 比未接种疫苗的 HCWs 更频繁地同意强制接种疫苗。需要更多考虑将强制性疫苗接种接受度作为主要结果的研究，但这项研究的结果证实，在某些情况下，大多数 HCWs 赞成强制性疫苗接种。这一点，再加上如果与具有类似症状的大流行重叠，流感流行可能产生的影响，需要重新考虑强制性疫苗接种。
