Department of Preventive Medicine, Institute of Health Sciences, College of Medicine, Gyeongsang National University, Jinju, Korea.
Center for Farmer's Safety and Health, Gyeongsang National University Hospital, Jinju, Korea.
BMC Geriatr. 2021 Jan 19;21(1):69. doi: 10.1186/s12877-021-02022-2.
The purpose of this study was to investigate the prevalence of osteosarcopenia in the over 60-year-old community and to evaluate whether osteosarcopenia is associated with disability, frailty and depression.
This study was performed using the baseline data of Namgaram-2, among the 1010 surveyed subjects, 885 study subjects who were 60 years or older and had all necessary tests performed were selected. The Kaigo-Yobo checklist (frailty), World Health Organization Disability Assessment Schedule (WHODAS) and Geriatric Depression Scale-Short Form-Korean (GDSSF-K) were used. The Asian Working Group for Sarcopenia (AWGS 2019) were applied in this study. Osteopenia was measured using data from dual energy X-ray absorptiometry (DEXA) and osteopenia was diagnosed when the T-score was less than - 1.0. The study subjects were divided into four groups: the normal group, in which both sarcopenia and osteopenia were undiagnosed, osteopenia only, sarcopenia only and the osteosarcopenia group, which was diagnosed with both sarcopenia and osteopenia.
Of the 885 subjects over 60 years old evaluated, the normal group comprised 34.0%, the only osteopenia group 33.7%, the only sarcopenia group 13.1%, and the osteosarcopenia group 19.2%. WHODAS (17.5, 95% CI: 14.8-20.1), Kaigo-Yobo (3.0, 95% CI: 2.6-3.4), and GDSSF mean score (4.6, 95% CI: 3.9-5.4) were statistically significantly higher in the osteosarcopenia group compared the other groups. Partial eta squared (η) of WHODAS (0.199) and Kaigo-Yobo (0.148) values according to Osteosarcopenia were large, and GDSSF (0.096) was medium CONCLUSIONS: Osteosarcopenia is a relatively common disease group in the older adults community that may cause deterioration of health outcomes. Therefore, when evaluating osteopenia or sarcopenia in the older adults, management of those in both disease groups should occur together.
本研究旨在调查社区中 60 岁以上人群中骨肌减少症的患病率,并评估骨肌减少症是否与残疾、衰弱和抑郁有关。
本研究使用 Namgaram-2 的基线数据,在调查的 1010 名受试者中,选择了 885 名 60 岁或以上且完成了所有必要检查的研究对象。使用了老年虚弱表(Kaigo-Yobo 检查表)(衰弱)、世界卫生组织残疾评估量表(WHODAS)和简易老年抑郁量表-韩国版(GDSSF-K)。本研究应用了亚洲肌肉减少症工作组(AWGS 2019)。骨密度使用双能 X 线吸收法(DEXA)数据进行测量,当 T 评分小于-1.0 时诊断为骨质疏松症。研究对象分为四组:正常组,既未诊断出肌少症也未诊断出骨质疏松症;单纯骨质疏松症组;单纯肌少症组;以及同时诊断出肌少症和骨质疏松症的骨肌减少症组。
在评估的 885 名 60 岁以上的受试者中,正常组占 34.0%,单纯骨质疏松症组占 33.7%,单纯肌少症组占 13.1%,骨肌减少症组占 19.2%。WHODAS(17.5,95%CI:14.8-20.1)、Kaigo-Yobo(3.0,95%CI:2.6-3.4)和 GDSSF 平均分(4.6,95%CI:3.9-5.4)在骨肌减少症组显著高于其他组。WHODAS(0.199)和 Kaigo-Yobo(0.148)根据骨肌减少症的部分 eta 平方(η)值较大,而 GDSSF(0.096)为中等。
骨肌减少症是老年人社区中一种较为常见的疾病群体,可能导致健康结局恶化。因此,在评估老年人的骨质疏松症或肌少症时,应同时管理两种疾病群体的患者。