Center for Neuromodulation in Depression and Stress, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Wiley Interdiscip Rev Cogn Sci. 2021 Jul;12(4):e1553. doi: 10.1002/wcs.1553. Epub 2021 Jan 19.
Combining transcranial magnetic stimulation (TMS) with functional magnetic resonance imaging offers an unprecedented tool for studying how brain networks interact in vivo and how repetitive trains of TMS modulate those networks among patients diagnosed with affective disorders. TMS compliments neuroimaging by allowing the interrogation of causal control among brain circuits. Together with TMS, neuroimaging can provide valuable insight into the mechanisms underlying treatment effects and downstream circuit communication. Here we provide a background of the method, review relevant study designs, consider methodological and equipment options, and provide statistical recommendations. We conclude by describing emerging approaches that will extend these tools into exciting new applications. This article is categorized under: Psychology > Emotion and Motivation Psychology > Theory and Methods Neuroscience > Clinical Neuroscience.
经颅磁刺激（TMS）与功能磁共振成像相结合，为研究大脑网络在体内如何相互作用以及重复的 TMS 刺激如何在患有情感障碍的患者中调节这些网络提供了前所未有的工具。TMS 通过允许在大脑回路之间进行因果控制的询问，补充了神经影像学。与 TMS 一起，神经影像学可以为治疗效果和下游回路通信的机制提供有价值的见解。在这里，我们提供了该方法的背景，回顾了相关的研究设计，考虑了方法和设备选择，并提供了统计建议。最后，我们描述了新兴的方法，这些方法将把这些工具扩展到令人兴奋的新应用中。本文属于以下类别：心理学 > 情绪与动机心理学 > 理论与方法神经科学 > 临床神经科学。
