Furman J M, Eidelman B H, Fromm G H
Department of Otolaryngology, University of Pittsburgh, PA.
Neurology. 1988 Mar;38(3):499-501. doi: 10.1212/wnl.38.3.499.
We report two women with ocular flutter and saccadic intrusions, documented by electro-oculography, who had complete spontaneous remission of their ocular motor findings prior to the appearance of a primary neoplastic process remote from the nervous system. Transient elevation of blood HVA and VMA levels was detected in one patient who subsequently had breast cancer. These cases indicate that spontaneous remission of saccadic oscillations does not necessarily imply a benign outcome. Patients with this ocular motor abnormality should be followed closely for signs of a remote neoplasm even if initial investigation is negative.
我们报告了两名患有眼球扑动和眼球跳动性侵入的女性，通过眼电图记录证实，她们在远离神经系统的原发性肿瘤形成之前，眼部运动症状完全自发缓解。在一名随后患乳腺癌的患者中检测到血液中高香草酸（HVA）和香草扁桃酸（VMA）水平短暂升高。这些病例表明，眼球跳动性振荡的自发缓解并不一定意味着预后良好。即使初始检查结果为阴性，对于有这种眼部运动异常的患者也应密切随访，以寻找远处肿瘤的迹象。
