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同卵双生子对照研究欺负受害与青少年时期自残和自杀未遂的关联。

A Co-Twin Control Study of the Association Between Bullying Victimization and Self-Harm and Suicide Attempt in Adolescence.

机构信息

Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana.

Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.

出版信息

J Adolesc Health. 2021 Aug;69(2):272-279. doi: 10.1016/j.jadohealth.2020.11.018. Epub 2021 Jan 19.

Abstract

PURPOSE

The aim of the study was to investigate the magnitude of an independent association between bullying victimization and self-harm and suicide attempt in adolescence after adjusting for unmeasured and measured confounding factors.

METHODS

Using the Child and Adolescent Twin Study in Sweden, we examined twins born between 1994 and 1999 (n = 13,852). Twins self-reported bullying victimization at age 15 years and self-harm and suicide attempt at age 18 years. We created a factor score of 13 bullying items, on which self-harm and suicide attempt items were regressed in three models: (1) among unrelated individuals; (2) among co-twins, in which a twin exposed to more bullying was compared with his/her co-twin who was exposed to less; and (3) among co-twins while adjusting for indicators of childhood psychopathology.

RESULTS

Among unrelated individuals, a one standard deviation increase in bullying victimization was associated with increased odds for self-harm (odds ratio [OR], 1.29 [95% confidence interval, 1.23-1.36]) and suicide attempt (OR, 1.68 [1.53-1.85]). Among co-twins, the odds attenuated for self-harm (OR, 1.19 [1.09-1.30]) and suicide attempt (OR, 1.39 [1.17-1.66]). Finally, when accounting for childhood psychopathology, there was a 14% (1.04-1.25) and 25% (1.03-1.52) relative increase in odds of self-harm and suicide attempt, respectively.

CONCLUSIONS

The results suggest that bullying victimization was uniquely associated with self-harm and suicide attempt over and above the confounding because of unmeasured and measured factors (i.e., familial vulnerability and pre-existing psychopathy). However, magnitudes were small, suggesting that additional interventions and screenings are needed to address suicidality apart from bullying interventions.

摘要

目的

本研究旨在调查在调整未测量和已测量的混杂因素后,青少年时期遭受欺凌与自残和自杀企图之间存在独立关联的程度。

方法

利用瑞典儿童和青少年双胞胎研究,我们检查了 1994 年至 1999 年出生的双胞胎(n=13852)。双胞胎在 15 岁时自我报告遭受欺凌的情况,在 18 岁时自我报告自残和自杀企图的情况。我们创建了一个包含 13 项欺凌项目的因子得分,在三个模型中回归了自残和自杀企图项目:(1)在无关个体中;(2)在同卵双胞胎中,将暴露于更多欺凌的双胞胎与其暴露于较少欺凌的同卵双胞胎进行比较;(3)在调整儿童期精神病理学指标的情况下,在同卵双胞胎中进行比较。

结果

在无关个体中,欺凌受害者的标准偏差增加 1 个单位与自残的几率增加相关(比值比[OR],1.29[95%置信区间,1.23-1.36])和自杀企图(OR,1.68[1.53-1.85])。在同卵双胞胎中,几率对于自残(OR,1.19[1.09-1.30])和自杀企图(OR,1.39[1.17-1.66])减弱。最后,当考虑到儿童期精神病理学时,自残和自杀企图的几率分别有 14%(1.04-1.25)和 25%(1.03-1.52)的相对增加。

结论

结果表明,欺凌受害者与自残和自杀企图之间存在独特的关联,超过了未测量和已测量因素(即家族易感性和已存在的精神病理学)造成的混杂。然而,幅度较小,表明除了欺凌干预外,还需要额外的干预和筛查来解决自杀问题。

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