Department of Biomedical Engineering, Columbia University Fu Foundation School of Engineering and Applied Science, 3227 Broadway, New York, NY, 10027, USA.
Department of Radiology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Sci Rep. 2021 Jan 22;11(1):2094. doi: 10.1038/s41598-021-81193-9.
In vivo magnetic resonance spectroscopy (MRS) is a powerful tool for biomedical research and clinical diagnostics, allowing for non-invasive measurement and analysis of small molecules from living tissues. However, currently available MRS processing and analytical software tools are limited in their potential for in-depth quality management, access to details of the processing stream, and user friendliness. Moreover, available MRS software focuses on selected aspects of MRS such as simulation, signal processing or analysis, necessitating the use of multiple packages and interfacing among them for biomedical applications. The freeware INSPECTOR comprises enhanced MRS data processing, simulation and analytical capabilities in a one-stop-shop solution for a wide range of biomedical research and diagnostic applications. Extensive data handling, quality management and visualization options are built in, enabling the assessment of every step of the processing chain with maximum transparency. The parameters of the processing can be flexibly chosen and tailored for the specific research problem, and extended confidence information is provided with the analysis. The INSPECTOR software stands out in its user-friendly workflow and potential for automation. In addition to convenience, the functionalities of INSPECTOR ensure rigorous and consistent data processing throughout multi-experiment and multi-center studies.
体内磁共振波谱（MRS）是生物医学研究和临床诊断的有力工具，可用于非侵入性地测量和分析活体组织中的小分子。然而，目前可用的 MRS 处理和分析软件工具在深入的质量管理、访问处理流程细节和用户友好性方面的潜力有限。此外，现有的 MRS 软件专注于 MRS 的某些方面，如模拟、信号处理或分析，因此需要使用多个软件包并在它们之间进行接口，以用于生物医学应用。免费软件 INSPECTOR 包含增强的 MRS 数据处理、模拟和分析功能，是各种生物医学研究和诊断应用的一站式解决方案。内置了广泛的数据处理、质量管理和可视化选项，可实现处理链中每一步的最大透明度评估。可以灵活选择和调整处理参数，以适应特定的研究问题，并提供扩展的置信信息分析。INSPECTOR 软件在用户友好的工作流程和自动化潜力方面表现出色。除了方便之外，INSPECTOR 的功能还确保了多实验和多中心研究中严格一致的数据处理。
